Results 101 to 110 of about 223 (129)

Drug Formulation of Securigera securidaca Seed Extracts

open access: yesProcesses, 2023
S. securidaca seeds are reported to treat a variety of diseases; they contain multiple antidiabetic constituents and are widely used as anti-hyperglycemic, antibacterial, as well as anti-hyperlipidemic agents. The present work aimed to propose tablet formulations containing extracts of S.
Ghassab M Al-Mazaideh   +2 more
exaly   +3 more sources

Securigenin glycosides as hypoglycemic principles of Securigera securidaca seeds

open access: yesJournal of Natural Medicines, 2016
Seeds of Securigera securidaca (Fabaceae) are used in Iranian folk medicine as an antidiabetic treatment. In this study, the antihyperglycemic activity of chloroform and methanol fractions (CF and MF) from S. securidaca seed extract was investigated and their bioactive constituents were identified. The antidiabetic effects of fractions were assessed by
Zahra Tofighi   +2 more
exaly   +6 more sources

Exploring Securigera securidaca Seeds as a Source of Potential CDK1 Inhibitors: Identification of Hippeastrine and Naringenin as Promising Hit Candidates

open access: yesProcesses, 2023
CDK1 (cyclin dependent kinase 1) is a key regulator of the cell cycle and is frequently dysregulated in cancer, making it a promising target for anticancer therapy. Securigera securidaca L. (S. securidaca) seeds, traditionally used in folk medicine for various ailments including cancer, were examined for their potential as CDK1/Cks2 inhibitors using in
Ghassab M Al-Mazaideh   +2 more
exaly   +3 more sources

Antinociceptive Effects of an Extract of Securigera securidaca and Their Mechanisms in Mice [PDF]

open access: yesNeurophysiology, 2013
We examined the effects of an aqueous extract from seeds of Securigera securidaca L. (S. s.), a plant used in folk medicine, on experimentally induced pain in balb-c mice. The tail-flick test (somatic pain evoked by thermonociceptive stimulation) and writhing test (visceral pain after i.p. injections of acetic acid) were used.
Siamak Shahidi
exaly   +3 more sources

The Influence of Securigera securidaca on Diabetes Management in Animal Models: A Systematic Review

open access: yesJournal of Advances in Medical and Biomedical Research, 2023
Abstract:   Background and Objective: It has been reported that allopathic drugs do not have significant effects on diabetes treatment. In contemporary literature, much attention has been given to the potential use of traditional medicines, including medicinal plants, in the treatment of metabolic abnormalities.
Zahra Nasehi   +2 more
exaly   +2 more sources
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Potent cytotoxic flavonoids from Iranian Securigera securidaca

Medicinal Chemistry Research, 2013
The seeds of Securigera securidaca (Fabaceae) were used for treatment of diabetes in folk medicine of Iran. In this study the cytotoxicity of different fractions of seeds extract led to purification of potent cytotoxic flavonoids. In the examination of cytotoxicity with brine shrimp lethality test method petroleum ether and chloroform fractions and ...
Zahra Tofighi   +2 more
exaly   +2 more sources

Antidiabetic and Antilipidemic Effects of Some Polar and Nonpolar Extracts of Securigera Securidaca Flowers

Pharmaceutical Chemistry Journal, 2016
Medicinal plants are widely used for pharmacological agents. These herbs are very rich sources of bioactive compounds. Securigera securidaca is reputed in folk medicine as antidiabetic and antilipidemic drug. In this research, the effect of solvent’s polarity in bioactive extract of this plant was evaluated by GC/MS analysis.
Abbas Ahmadi   +2 more
exaly   +2 more sources

Antidiabetic Activity of Aqueous Seed Extract of Securigera securidaca in Streptozotocin Induced Diabetic Rats [PDF]

open access: yesJournal of Advances in Medical and Biomedical Research, 2019
Background & Objective: Securigera securidaca is a medicinal plant used in Persian folk medicine to decrease blood sugar. Nevertheless, there is some controversy about its effects. The current study investigated the hypoglycemic activity of the aqueous seed extract of S. securidaca.
Mohammad Azadbakht   +2 more
exaly   +2 more sources

The Effect of Spraying with the Hormone Brassinolide on the Production of Oil and Glycosides of Goat Pea (Securigera securidaca)

open access: yesIOP Conference Series: Earth and Environmental Science, 2023
Abstract A field experiment was carried out in Diyala Governorate during the winter season 2020-2021 to evaluate the effect of spraying three concentrations of Brassinolide hormone (1, 2 and 3 ppm) in addition to the control treatment (0 ppm) and three dates of spraying (after 20,40 and 60 days of germination) in the production of oil ...
exaly   +2 more sources

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