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Potent cytotoxic flavonoids from Iranian Securigera securidaca
Medicinal Chemistry Research, 2014The seeds of Securigera securidaca (Fabaceae) were used for treatment of diabetes in folk medicine of Iran. In this study the cytotoxicity of different fractions of seeds extract led to purification of potent cytotoxic flavonoids. In the examination of cytotoxicity with brine shrimp lethality test method petroleum ether and chloroform fractions and ...
Z. Tofighi +5 more
semanticscholar +2 more sources
Securigenin glycosides as hypoglycemic principles of Securigera securidaca seeds
Journal of Natural Medicines, 2016 Seeds of Securigera securidaca (Fabaceae) are used in Iranian folk medicine as an antidiabetic treatment. In this study, the antihyperglycemic activity of chloroform and methanol fractions (CF and MF) from S. securidaca seed extract was investigated and their bioactive constituents were identified. The antidiabetic effects of fractions were assessed by
Zahra Tofighi +8 more
semanticscholar +5 more sources
Drug Research, 2015
The search for indigenous natural antidiabetic and antilipidemec agents is still ongoing. Medicinal plants are widely used for this purpose. These herbs are very rich sources of bioactive compounds as flavonoids, polyphenols, tannins, alkaloids which have been reported as effective role to reduce blood glucose and lipid levels.
A. Ahmadi +3 more
semanticscholar +3 more sources
The search for indigenous natural antidiabetic and antilipidemec agents is still ongoing. Medicinal plants are widely used for this purpose. These herbs are very rich sources of bioactive compounds as flavonoids, polyphenols, tannins, alkaloids which have been reported as effective role to reduce blood glucose and lipid levels.
A. Ahmadi +3 more
semanticscholar +3 more sources
Pharmaceutical Chemistry Journal, 2016
Medicinal plants are widely used for pharmacological agents. These herbs are very rich sources of bioactive compounds. Securigera securidaca is reputed in folk medicine as antidiabetic and antilipidemic drug. In this research, the effect of solvent’s polarity in bioactive extract of this plant was evaluated by GC/MS analysis.
A. Ahmadi +3 more
semanticscholar +2 more sources
Medicinal plants are widely used for pharmacological agents. These herbs are very rich sources of bioactive compounds. Securigera securidaca is reputed in folk medicine as antidiabetic and antilipidemic drug. In this research, the effect of solvent’s polarity in bioactive extract of this plant was evaluated by GC/MS analysis.
A. Ahmadi +3 more
semanticscholar +2 more sources