Results 41 to 50 of about 5,525,844 (353)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

A Survey of Physical Layer Security Techniques for 5G Wireless Networks and Challenges Ahead [PDF]

, 2018
Physical layer security which safeguards data confidentiality based on the information-theoretic approaches has received significant research interest recently.
Caire, Giuseppe, Gao, Xiqi, Khisti, Ashish, Wong, Kai-Kit, Wu, Yongpeng, Xiao, Chengshan   +5 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Immune cell population dynamics following neonatal BCG vaccination and aerosol BCG revaccination in rhesus macaques

Scientific Reports
The BCG vaccine is given to millions of children globally but efficacy wanes over time and differences in the immune systems between infants and adults can influence vaccine efficacy.
Laura Sibley, Charlotte Sarfas, Alexandra L. Morrison, Jessica Williams, Konstantinos Gkolfinos, Adam Mabbutt, William Eckworth, Steve Lawrence, Mike Dennis, Andrew White, Sally Sharpe   +10 more
doaj   +1 more source

Ureteral tumor in an ectopic duplex system: a case report

Journal of Medical Case Reports, 2019
Introduction Ureteral ectopia is a rarely observed anomaly. It may be totally asymptomatic. An association with a duplex system is exceptional. Diagnostic and therapeutic approaches are challenging. Carcinologic surgery must consider the anatomic variant,
Omar Karray, Hassen Khouni, Mahdi Charfi, Rami Boulma, Mehdi Debaibi, Rym Makhlouf, Karim Bargaoui, Oumeima Nessej, Azza Seridi, Slim Fourti, Mohamed Habib Bouhaouala, Adnene Chouchene   +11 more
doaj   +1 more source

A Framework for Analyzing Fraud Risk Warning and Interference Effects by Fusing Multivariate Heterogeneous Data: A Bayesian Belief Network

Entropy, 2023
In the construction of a telecom-fraud risk warning and intervention-effect prediction model, how to apply multivariate heterogeneous data to the front-end prevention and management of telecommunication network fraud has become one of the focuses of this
Mianning Hu, Xin Li, Mingfeng Li, Rongchen Zhu, Binzhou Si   +4 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Effectiveness and user experience of nose and throat swabbing techniques for SARS-CoV-2 detection: results from the UK COVID-19 National Testing Programme

BMC Global and Public Health
Background The UK’s National Health Service Test and Trace (NHSTT) program aimed to provide the most effective and accessible SARS-CoV-2 testing approach possible.
Matthias E. Futschik, Raghavendran Kulasegaran-Shylini, Edward Blandford, Sean Harper, David Chapman, Elena Turek, Somya Agrawal, Valerie Phillips, Hannah Fordham, Lee Chan, Mike Kidd, Andrew Dodgson, Paul E. Klapper, Malur Sudhanva, Richard Vipond, Susan Hopkins, Tim Peto, Sarah Tunkel, Tom Fowler   +18 more
doaj   +1 more source

Deepfake Detection Algorithm Based on Dual-Branch Data Augmentation and Modified Attention Mechanism

Applied Sciences, 2023
Mainstream deepfake detection algorithms generally fail to fully extract forgery traces and have low accuracy when detecting forged images with natural corruptions or human damage.
Da Wan, Manchun Cai, Shufan Peng, Wenkai Qin, Lanting Li   +4 more
doaj   +1 more source