Results 41 to 50 of about 4,851,518 (333)

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Secure Composition of Robust and Optimising Compilers [PDF]

open access: yesarXiv, 2023
To ensure that secure applications do not leak their secrets, they are required to uphold several security properties such as spatial and temporal memory safety as well as cryptographic constant time. Existing work shows how to enforce these properties individually, in an architecture-independent way, by using secure compiler passes that each focus on ...
arxiv  

Deepfake Detection Algorithm Based on Dual-Branch Data Augmentation and Modified Attention Mechanism

open access: yesApplied Sciences, 2023
Mainstream deepfake detection algorithms generally fail to fully extract forgery traces and have low accuracy when detecting forged images with natural corruptions or human damage.
Da Wan   +4 more
doaj   +1 more source

5th Annual Progress Reporting and Coordination Meeting on CCAFS Projects and Regional Activities in Southeast Asia [PDF]

open access: yes, 2020
The proceedings document the results of the 5th Annual Progress Reporting and Coordination Meeting on CCAFS Projects and Regional Activities in Southeast Asia.
CGIAR Research Program on Climate Change, Agriculture and Food Security
core  

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Secure physical layer network coding versus secure network coding [PDF]

open access: yesEntropy, 24(1), 47 (2022), 2018
Secure network coding realizes the secrecy of the message when the message is transmitted via noiseless network and a part of edges or a part of intermediate nodes are eavesdropped. In this framework, if the channels of the network has noise, we apply the error correction to noisy channel before applying the secure network coding.
arxiv   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Immune cell population dynamics following neonatal BCG vaccination and aerosol BCG revaccination in rhesus macaques

open access: yesScientific Reports
The BCG vaccine is given to millions of children globally but efficacy wanes over time and differences in the immune systems between infants and adults can influence vaccine efficacy.
Laura Sibley   +10 more
doaj   +1 more source

Evaluating a Potential US-China Bilateral Investment Treaty: Background, Context and Implications [PDF]

open access: yes, 2010
[Excerpt] This paper, prepared by the Economist Intelligence Unit for the US-China Economic and Security Council, summarises the context, current discussions and implications of a potential US-China bilateral investment treaty (BIT).
US-China Economic and Security Review Commission
core   +1 more source

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