Results 51 to 60 of about 1,864,674 (318)
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Texas National Security Review: Shaping Security Vol. 8, Issue 4, 2025
TABLE OF CONTENTS: THE FOUNDATION pg.2 What Do We Really Know? By Francis J. Gavin THE SCHOLAR Pg.8 Hard Then, Harder Now: CoCom’s Lessons and the Challenge of Crafting Effective Export Controls Against China by Jennifer Lind and Michael Mastanduno ...
Texas National Security Review
core +1 more source
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
How Proverbs Damage Homeland Security [PDF]
This article appeared in Homeland Security Affairs (September 2011), v.7 no.2"Christopher Bellavita discusses twelve proverbs -- accepted truths -- that have characterized the homeland security narrative.
Bellavita, Christopher
core
Nevada National Security Site 2010 Waste Management Monitoring Report Area 3 and Area 5 Radioactive Waste Management Sites [PDF]
Environmental monitoring data were collected at and around the Area 3 and Area 5 Radioactive Waste Management Sites (RWMSs) at the Nevada National Security Site (NNSS).
National Security Technologies, LLC
core +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Background Shiga toxin-producing Escherichia coli (STEC) infections are a significant public health concern as they can cause serious illness and outbreaks.
Amoolya Vusirikala +12 more
doaj +1 more source
Measuring the Human Factor of Cyber Security [PDF]
This article appeared in Homeland Security Affairs (May 2012), supplement 5, article 2"This paper investigates new methods to measure, quantify and evaluate the security posture of human organizations especially within large corporations and government ...
Stolfo, Salvatore J. +6 more
core +1 more source
This chapter first defines the concept of economic security and goes on to identify the main concerns of the EU and Asia in this domain. It explains why Asia cannot be apprehended as a homogenous block and provides a taxonomy of the Asian economies according to their specificities in order to compare their approach to economic security to the EU’s.
Defraigne, Jean-Christophe +1 more
openaire +4 more sources

