Results 51 to 60 of about 1,864,674 (318)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Texas National Security Review: Shaping Security Vol. 8, Issue 4, 2025

open access: yes
TABLE OF CONTENTS: THE FOUNDATION pg.2 What Do We Really Know? By Francis J. Gavin THE SCHOLAR Pg.8 Hard Then, Harder Now: CoCom’s Lessons and the Challenge of Crafting Effective Export Controls Against China by Jennifer Lind and Michael Mastanduno ...
Texas National Security Review
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

How Proverbs Damage Homeland Security [PDF]

open access: yes, 2011
This article appeared in Homeland Security Affairs (September 2011), v.7 no.2"Christopher Bellavita discusses twelve proverbs -- accepted truths -- that have characterized the homeland security narrative.
Bellavita, Christopher
core  

Nevada National Security Site 2010 Waste Management Monitoring Report Area 3 and Area 5 Radioactive Waste Management Sites [PDF]

open access: yes, 2011
Environmental monitoring data were collected at and around the Area 3 and Area 5 Radioactive Waste Management Sites (RWMSs) at the Nevada National Security Site (NNSS).
National Security Technologies, LLC
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Facilitators and barriers to implementing successful exclusion among children with shiga toxin-producing Escherichia coli: a qualitative analysis of public health case management records

open access: yesBMC Public Health
Background Shiga toxin-producing Escherichia coli (STEC) infections are a significant public health concern as they can cause serious illness and outbreaks.
Amoolya Vusirikala   +12 more
doaj   +1 more source

Measuring the Human Factor of Cyber Security [PDF]

open access: yes, 2011
This article appeared in Homeland Security Affairs (May 2012), supplement 5, article 2"This paper investigates new methods to measure, quantify and evaluate the security posture of human organizations especially within large corporations and government ...
Stolfo, Salvatore J.   +6 more
core   +1 more source

Economic Security

open access: yes, 2021
This chapter first defines the concept of economic security and goes on to identify the main concerns of the EU and Asia in this domain. It explains why Asia cannot be apprehended as a homogenous block and provides a taxonomy of the Asian economies according to their specificities in order to compare their approach to economic security to the EU’s.
Defraigne, Jean-Christophe   +1 more
openaire   +4 more sources

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