Results 41 to 50 of about 5,288,295 (302)

Immune cell population dynamics following neonatal BCG vaccination and aerosol BCG revaccination in rhesus macaques

Scientific Reports
The BCG vaccine is given to millions of children globally but efficacy wanes over time and differences in the immune systems between infants and adults can influence vaccine efficacy.
Laura Sibley, Charlotte Sarfas, Alexandra L. Morrison, Jessica Williams, Konstantinos Gkolfinos, Adam Mabbutt, William Eckworth, Steve Lawrence, Mike Dennis, Andrew White, Sally Sharpe   +10 more
doaj   +1 more source

Ureteral tumor in an ectopic duplex system: a case report

Journal of Medical Case Reports, 2019
Introduction Ureteral ectopia is a rarely observed anomaly. It may be totally asymptomatic. An association with a duplex system is exceptional. Diagnostic and therapeutic approaches are challenging. Carcinologic surgery must consider the anatomic variant,
Omar Karray, Hassen Khouni, Mahdi Charfi, Rami Boulma, Mehdi Debaibi, Rym Makhlouf, Karim Bargaoui, Oumeima Nessej, Azza Seridi, Slim Fourti, Mohamed Habib Bouhaouala, Adnene Chouchene   +11 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Effectiveness and user experience of nose and throat swabbing techniques for SARS-CoV-2 detection: results from the UK COVID-19 National Testing Programme

BMC Global and Public Health
Background The UK’s National Health Service Test and Trace (NHSTT) program aimed to provide the most effective and accessible SARS-CoV-2 testing approach possible.
Matthias E. Futschik, Raghavendran Kulasegaran-Shylini, Edward Blandford, Sean Harper, David Chapman, Elena Turek, Somya Agrawal, Valerie Phillips, Hannah Fordham, Lee Chan, Mike Kidd, Andrew Dodgson, Paul E. Klapper, Malur Sudhanva, Richard Vipond, Susan Hopkins, Tim Peto, Sarah Tunkel, Tom Fowler   +18 more
doaj   +1 more source

Security Rules versus Security Properties [PDF]

, 2010
There exist many approaches to specify and to define security policies. We present here a framework in which the basic components of security policies can be expressed, and we identify their role in the description of a policy, of a system and of a secure system.
openaire   +1 more source

Global Health Security: Security for whom? Security from what? [PDF]

Political Studies, 2011
The concept of ‘health security’ has been increasingly apparent in recent years in both academic and policy discourses on transborder infectious disease threats. Yet it has been noted that there are a range of conceptualisations of ‘health security’ in circulation and that confusion over the concept is creating international tensions with some states (
openaire   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Human security as ‘Ethnic Security’ in Kosovo [PDF]

, 2010
In Kosovo, the concept of human security is invoked in a three-fold manner. First of all, the international community has applied human security for the purpose of maintaining a fragile peace and stability in Kosovo.
Beha, Adem, Visoka, Gëzim
core  

Towards Security Goals in Summative E-Assessment Security

, 2009
The general security goals of a computer system are known to include confidentiality, integrity and availability (C-I-A) which prevent critical assets from potential threats.
Apampa, K.M, Argles, D, Wills, G.B
core   +1 more source