Results 51 to 60 of about 7,114,774 (349)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Impact of climate change on biodiversity and food security: a global perspective—a review article

open access: yesAgriculture & Food Security, 2021
Climate change is happening due to natural factors and human activities. It expressively alters biodiversity, agricultural production, and food security. Mainly, narrowly adapted and endemic species are under extinction.
M. Muluneh
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Immune cell population dynamics following neonatal BCG vaccination and aerosol BCG revaccination in rhesus macaques

open access: yesScientific Reports
The BCG vaccine is given to millions of children globally but efficacy wanes over time and differences in the immune systems between infants and adults can influence vaccine efficacy.
Laura Sibley   +10 more
doaj   +1 more source

Ureteral tumor in an ectopic duplex system: a case report

open access: yesJournal of Medical Case Reports, 2019
Introduction Ureteral ectopia is a rarely observed anomaly. It may be totally asymptomatic. An association with a duplex system is exceptional. Diagnostic and therapeutic approaches are challenging. Carcinologic surgery must consider the anatomic variant,
Omar Karray   +11 more
doaj   +1 more source

COVID-19 implications on household income and food security in Kenya and Uganda: Findings from a rapid assessment

open access: yesWorld Development, 2020
Highlights • We assessed COVID-19 implications on household income and food security using in Kenya and Uganda.• More than two-thirds of households experienced income shocks and worsened food security.• Food security outcomes were worse among the income ...
M. Kansiime   +5 more
semanticscholar   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Security and Privacy on Blockchain [PDF]

open access: yesACM Computing Surveys, 2019
Blockchain offers an innovative approach to storing information, executing transactions, performing functions, and establishing trust in an open environment.
Rui Zhang, Rui Xue, Ling Liu
semanticscholar   +1 more source

A Survey of Physical Layer Security Techniques for 5G Wireless Networks and Challenges Ahead [PDF]

open access: yes, 2018
Physical layer security which safeguards data confidentiality based on the information-theoretic approaches has received significant research interest recently.
Caire, Giuseppe   +5 more
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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