FEBS Open Bio, EarlyView.The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao +23 more
wiley +1 more source
Bispectral index during remimazolam versus propofol sedation at matched depths: a randomized, double-blind crossover trial in healthy volunteers. [PDF]
Ann MedCai S +6 more
europepmc +1 more source
GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors
FEBS Open Bio, EarlyView.GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille +6 more
wiley +1 more source
Paediatric Procedural Sedation and Analgesia in Emergency Departments: A Delphi Consensus Study. [PDF]
Emerg Med AustralasCahís N +7 more
europepmc +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Recovery Profiles After MOAA/S-Guided Remifentanil- Versus Fentanyl-Based Propofol Sedation for Gastrointestinal Endoscopy: An IPTW-Adjusted Retrospective Cohort Study. [PDF]
J Clin MedTüzen AS +7 more
europepmc +1 more source
Rationally engineered polymeric interfaces for selective and dynamic recognition of vesicular agents
FEBS Open Bio, EarlyView.This review explores how molecularly imprinted polymers can be engineered to recognize complex nanoscale vesicles, including extracellular vesicles and membrane‐enveloped viruses. By tailoring polymer cavities to vesicle surface chemistry and structure, these synthetic receptors support selective detection, separation, and integration with optical ...
Özgecan Erdem +4 more
wiley +1 more source
Acclimatisation with Inhalation Sedation in Paediatric Dentistry: A Scoping Review. [PDF]
Dent J (Basel)Bowers EJ, Donnell CC.
europepmc +1 more source
FEBS Open Bio, EarlyView.Coating 3D‐printed PCL scaffolds with silk fibroin can improve biocompatibility and bone cell adhesion. One innovative design for tissue‐engineering scaffolds uses 3D printing technology. Here, we used polycaprolactone (PCL) filament as a biocompatible material to design a porous 3D scaffold for bone tissue engineering.
Hamed Koeini +7 more
wiley +1 more source