Results 251 to 260 of about 242,778 (310)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Precision Sedation for Gastrointestinal Endoscopy in Older Adults: Brain Vulnerability and Recovery. [PDF]

Drug Des Devel Ther
Qian H, Gu H, Zhu J, Chen K, Jiang P, Zheng L.   +5 more
europepmc   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Dose-conditioned machine-learning prediction of a composite target sedation state in patients undergoing propofol-sedated gastrointestinal endoscopy. [PDF]

Ann Med
Zhang H, Zhao L, Yang W, Li B, Lin W, Chen X, Mo L, Dai S, Chen W, Yang F, Ma H.   +10 more
europepmc   +1 more source

Current evidence of flexible ureteroscopic laser lithotripsy under local anesthesia: feasibility, safety, and clinical application. [PDF]

Front Med (Lausanne)
Chen H, Xing S, Shi S, Lai S.
europepmc   +1 more source

Effects of substance use on sedation requirements in critically ill patients. [PDF]

Ment Health Clin
Weger BR, Gignac L, Reneau SM, Booth A.
europepmc   +1 more source

Assessment: An Unresolved Intercurrent Event in a Randomized Trial of Ciprofol versus Propofol [Response to Letter]. [PDF]

Drug Des Devel Ther
Zhang Y, Wu L, Gao Z, Zhang M, Feng C, Zhang H, Zhang H, Liu B.   +7 more
europepmc   +1 more source

Association of Propofol Versus Midazolam Sedation With Successful Pharyngeal Observation During Upper Gastrointestinal Endoscopy: A Retrospective Study. [PDF]

DEN Open
Sumi K, Sato T, Sakurai T, Uehara K, Ishihara A, Ito T.   +5 more
europepmc   +1 more source

Enhancing Decision-Making in Pediatric Radiotherapy: Internal Validation and Expansion of the M.A.P.-RT Schedule for Sedation Need Prediction and Identification of Psychological Support Needs in a Prospective Cohort of 268 Pediatric Patients. [PDF]

Children (Basel)
Marconi E, Meldolesi E, Mariani S, Mauti M, Dinapoli N, Massaccesi M, Dinapoli L, Bernabucci L, Iacovone S, Turco G, Guido A, De Cristofaro D, Salvo A, Panza G, Stimato G, Ruggiero A, Mastronuzzi A, Zucchetti G, Cornacchione P, Frascino V, Tagliaferri L, Chieffo DPR, Gambacorta MA, Chiesa S.   +23 more
europepmc   +1 more source