Results 101 to 110 of about 100,774 (304)
We evaluated changes in the binding properties of sedative and non-sedative histamine H1–receptor antagonists induced by internalization of H1 receptors in intact human U373 MG astrocytoma cells.
Hiroshi Komazaki +4 more
core +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
4-Hydroxybenzyl alcohol derivatives and their sedative–hypnotic activities
2FHBA, a derivative of HBA, exerts sedative and hypnotic effects through the serotonergic and GABAergic systems.
Yan Zhao +6 more
core +1 more source
Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias +3 more
wiley +1 more source
Propofol‐alone sedative efficacy in observational biliopancreatic endoscopic ultrasound
Objectives Appropriate sedative and analgesic selection is essential to reduce patient discomfort and body movement to safely conduct endoscopic ultrasonography (EUS).
Hisaki Kato +8 more
doaj +1 more source
Medicinal plants for the "nerves": a review of ethnobotanical studies carried out in South Brazil
Among the medicinal purposes for which plants have been used is the treatment of “nerves". The objective of this study was to search for species of plants used in the state of Rio Grande do Sul (South Brazil) for the relief of symptoms related to central
Andressa Verdum Gross +4 more
doaj +1 more source
Structure-Dependent Activity of Natural GABA(A) Receptor Modulators
GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains.
Serhat Sezai Çiçek
doaj +1 more source
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source
Objectives A relationship between endoscopic submucosal dissection (ESD) and deep vein thrombosis has been recognized. We previously reported that a high corrected midazolam dose (total midazolam dose/initial dose of midazolam used to induce sedation) is
Fumito Harada +15 more
doaj +1 more source
The concept of ’Musa-pelo and the medicinal use of shrubby legumes (Fabaceae) in Lesotho
In the Kingdom of Lesotho, 20 plant species are commonly known as 'Musa-pelo. The term literally means ‘the one who brings back or tums around the heart’.
A. Moteetee, B-E. van Wyk
doaj +1 more source

