A Comparison of Moderate Oral Sedation Drug Regimens for Pediatric Dental Treatment: A Pilot Study [PDF]
Purpose: Compare moderate oral sedation of pediatric patients using Hydroxyzine and Meperidine with either Diazepam or Midazolam in management of pediatric dental patients. Methods: Randomized, double-blind, crossover pilot study of patients 3 to 7 years
Parikh, Ojas A
core +1 more source
Is there a potential of misuse for Magnolia officinalis compounds/metabolites? [PDF]
© 2017 John Wiley & Sons, Ltd.Objective: Magnolia bark contains magnolol, metabolized to tetrahydromagnolol and honokiol, with both GABA-ergic/cannabimimetic activities, hence of possible attraction to vulnerable individuals/recreational misusers ...
Alexeev+32 more
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Occurrence, Risk Factors, and Prognosis of Acute Cerebral Microinfarcts in CADASIL
ABSTRACT Introduction Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic cerebral small vessel disease in adults. This study investigates the occurrence, risk factors, and prognosis of acute cerebral microinfarcts (ACMIs) in patients with CADASIL.
Xuejiao Men+11 more
wiley +1 more source
Race/ethnicity and gender differences in drug use and abuse among college students [PDF]
This study examines race/ethnicity and gender differences in drug use and abuse for substances other than alcohol among undergraduate college students.
Boyd, Carol J.+5 more
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ABSTRACT Objective Sleep spindles are an electrophysiological fingerprint of the sleeping human brain. They can be described in terms of duration, frequency, amplitude, and density, and vary widely according to age and sex. Spindles play a role in sleep and wake functions and are altered in several neurological and psychiatric disorders.
Julien Coelho+8 more
wiley +1 more source
Comparison of Triple Combination Oral Sedation Regimens for Pediatric Dental Treatment [PDF]
Purpose: Compare the efficacy of two benzodiazepines (diazepam or midazolam) in combination with meperidine and hydroxyzine for pediatric dental sedation.
Henderson, Brett H
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Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor [PDF]
In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR).
Belelli, Delia+3 more
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CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu+12 more
wiley +1 more source
Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through a߿2-type GABA(A) Receptors [PDF]
Peer reviewedPublisher ...
Korpi, Esa R+6 more
core +3 more sources