Results 41 to 50 of about 195,235 (340)

Use of sedative-hypnotics and the risk of Alzheimer’s dementia: A retrospective cohort study

open access: yesPLoS ONE, 2018
There has been a growing interest in the relationship between sedative-hypnotics use and the risk of Alzheimer’s dementia (AD) risk. This study aimed to evaluate the risk of AD associated with the use of sedative-hypnotics.
Joonki Lee   +4 more
semanticscholar   +1 more source

The implausibility of ‘usual care’ in an open system: sedation and weaning practices in Paediatric Intensive Care Units (PICUs) in the United Kingdom (UK) [PDF]

open access: yes, 2015
Background: The power of the randomised controlled trial depends upon its capacity to operate in a closed system whereby the intervention is the only causal force acting upon the experimental group and absent in the control group, permitting a valid ...
B Ambuel   +34 more
core   +1 more source

Pharmacognostic Study and Sedative Activity of Bryophyllum pinnatum Stem Methanol Extract and Fractions

open access: yesSciences of Phytochemistry, 2023
Insomnia is known as sleep insufficiency and is considered a capital public health concern. Bryophyllum pinnatum which belongs to the family Grassulaceae is used in folkloric medicine to treat various kind of ailment.
Kosisochukwu Frances Okoye   +3 more
doaj   +1 more source

Assessing the Existence of Pharmaceutical Compounds in Hospital Treated Wastewater (Case Study: Sedatives in One of the Hospitals in District 11 of Tehran) [PDF]

open access: yesمحیط زیست و مهندسی آب, 2020
Hospital wastewater is one of the most infectious and dangerous wastewaters that may contain large amounts of pathogenic microorganisms, dangerous pollutants of various hormones.
Leila Rahimvand, Nooshin Sajadi
doaj   +1 more source

Sleep and Sedative States Induced by Targeting the Histamine and Noradrenergic Systems

open access: yesFront. Neural Circuits, 2018
Sedatives target just a handful of receptors and ion channels. But we have no satisfying explanation for how activating these receptors produces sedation. In particular, do sedatives act at restricted brain locations and circuitries or more widely?
Xiao Yu, N. Franks, W. Wisden
semanticscholar   +1 more source

Sedative and antinociceptive effects of different combinations of detomidine and methadone in standing horses [PDF]

open access: yes, 2017
Objective To evaluate intravenous (IV) detomidine with methadone in horses to identify a combination which provides sedation and antinociception without adverse effects. Study design Randomized, placebo-controlled, blinded, crossover.
Crosignani, N   +6 more
core   +2 more sources

Analysis of anticholinergic and sedative medicine effects on physical function, cognitive function, appetite and frailty: a cross-sectional study in Australia

open access: yesBMJ Open, 2019
Objective To test the association between use of medicines with anticholinergic or sedative properties and physical function, cognitive function, appetite and frailty.
R. Lim   +4 more
semanticscholar   +1 more source

Intermittent Bolus versus Continuous Infusion of Propofol for Deep Sedation during ABR/Nuclear Medicine Studies [PDF]

open access: yes, 2017
Objective  A comparison of intermittent bolus (IB) versus continuous infusion of propofol for deep sedation. Material and Methods  A retrospective review of patients sedated for Auditory Brainstem Response (ABR)/nuclear medicine studies between September
Ahmed, Sheikh Sohail   +3 more
core   +1 more source

A systematic review of the effects of sedatives and anesthetics in patients with obstructive sleep apnea

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2011
The objective of this review is to determine the effects of perioperative sedatives and anesthetics in surgical patients with obstructive sleep apnea (OSA) on respiratory events, medication requirements, hemodynamics, pain, emergence, and hospital stay ...
Saravanan Ankichetty   +2 more
doaj   +1 more source

In Vivo and In Vitro Biological Evaluation and Molecular Docking Studies of Compounds Isolated from Micromeria biflora (Buch. Ham. ex D.Don) Benth

open access: yesMolecules, 2022
Micromeria biflora, a traditional medicinal plant, is extensively used for treating various painful conditions, such as nose bleeds, wounds, and sinusitis.
Abdullah S. M. Aljohani   +4 more
doaj   +1 more source

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