Results 21 to 30 of about 145,536 (303)

Survey of Glasgow Coma Scale and PaO2/FIO2 ratio assessment methods for the Sequential Organ Failure Assessment score in Japanese intensive care units

Acute Medicine & Surgery, 2022
Aim Accurately calculating the Sequential Organ Failure Assessment (SOFA) score is essential for medical resource allocation and decision‐making. This study surveyed Japanese intensive care units regarding their assessment of the Glasgow Coma Scale (GCS)
Mitsuhiro Tamoto, Takumi Imai, Rei Aida, Yusuke Harada, Yuki Wakabayashi, Gaku Satone, Shunsuke Ichoda, Takeshi Unoki, Ayumi Shintani   +8 more
doaj   +1 more source

In vivo analgesic, muscle relaxant, sedative and toxicological studies of Senna bicapsularis (L.) Roxb

Journal of Taibah University for Science, 2021
Senna bicapsularis is an important medicinal plant that has been traditionally used as a purgative and muscle relaxant as well as for the treatment of pain.
Fahad A. Alhumaydhi
doaj   +1 more source

Sedative-like effect of intraperitoneal GABA administration in the open field test [PDF]

, 2016
Gamma-Amino Butyric Acid (GABA) is the main inhibitor neurotransmitter of the Central Nervous System (CNS). Its peripheral administration has been matter of discussion. On the one hand, it has been reported that it does not cross the Blood-Brain Barrier (
Gargiulo, Augusto Pascual Ítalo, Gargiulo, Pascual Angel, Guevara, Manuel Alejandro, Lafuente, José Vicente, Landa, Adriana Inés, Marquez Herrero, Santiago, Mesones, Humberto Luis, Romanowicz, Esteban Alejandro   +7 more
core   +1 more source

Comparing the Effect of Dexmedetomidine and Midazolam in Patients with Brain Injury

Brain Sciences, 2022
Background: Studies have shown that dexmedetomidine improves neurological function. Whether dexmedetomidine reduces mortality or improves quantitative electroencephalography (qEEG) among patients post-craniotomy remains unclear.
Yanxia Huang, Yunxin Deng, Renjing Zhang, Mei Meng, Dechang Chen   +4 more
doaj   +1 more source

The implausibility of ‘usual care’ in an open system: sedation and weaning practices in Paediatric Intensive Care Units (PICUs) in the United Kingdom (UK) [PDF]

, 2015
Background: The power of the randomised controlled trial depends upon its capacity to operate in a closed system whereby the intervention is the only causal force acting upon the experimental group and absent in the control group, permitting a valid ...
B Ambuel, B Blackwood, B Blackwood, B Blackwood, B Blackwood, Bronagh Blackwood, C Maloney, CJL Newth, D Bieri, D Macrae, DL Jackson, E Ista, E Ista, F Frutos-Vivar, FK Foronda, FW Moler, J Rycroft-Malone, J Rycroft-Malone, J Rycroft-Malone, JA Durlak, K Harron, L Kohn, L Rose, LS Franck, Lyvonne Tume, M Cunliffe, NJ Vet, P O’Halloran, PA Jouvet, RP Dellinger, S Chawla, S Playfor, SI Merkel, SW Krechel, YN Poh   +34 more
core   +1 more source

Pharmacognostic Study and Sedative Activity of Bryophyllum pinnatum Stem Methanol Extract and Fractions

Sciences of Phytochemistry, 2023
Insomnia is known as sleep insufficiency and is considered a capital public health concern. Bryophyllum pinnatum which belongs to the family Grassulaceae is used in folkloric medicine to treat various kind of ailment.
Kosisochukwu Frances Okoye, Fredrick Chinedu Anowi, InnocentMary IfedibaluChukwu Ejiofor, Olanrewaju Mary Ololade   +3 more
doaj   +1 more source

Sedative and anxiolytic effects of Capparis sicula Duhamel: in vivo and in silico approaches with phytochemical profiling

Frontiers in Pharmacology
The World Health Organization reports that 30% of adults worldwide suffer from insomnia, while 10% of people worldwide suffer with various forms of anxiety.
Büşra Karpuz Ağören, Esra Küpeli Akkol, Ismail Çelik, Eduardo Sobarzo-Sánchez, Eduardo Sobarzo-Sánchez   +4 more
doaj   +1 more source

Structure-Dependent Activity of Natural GABA(A) Receptor Modulators

Molecules, 2018
GABA(A) receptors are ligand-gated ion channels consisting of five subunits from eight subfamilies, each assembled in four hydrophobic transmembrane domains.
Serhat Sezai Çiçek
doaj   +1 more source

Euthanasia Considered as Device Paradigm [PDF]

, 1997
In this paper I take as my point of departure the way euthanasia has been legally settled in the Netherlands. My concern is not with the question whether euthanasia is morally or religiously acceptable.
Tijmes, Pieter
core   +3 more sources

The concept of ’Musa-pelo and the medicinal use of shrubby legumes (Fabaceae) in Lesotho

Bothalia: African Biodiversity & Conservation, 2007
In the Kingdom of Lesotho, 20 plant species are commonly known as  'Musa-pelo. The term literally means ‘the one who brings back or tums around the heart’.
A. Moteetee, B-E. van Wyk
doaj   +1 more source