Results 11 to 20 of about 145,536 (303)
LC-MS Characterization and Biological Activities of Cuban Cultivars of Plectranthus neochilus Schltr
Plants, 2022 Plectranthus neochilus Schltr. (Lamiaceae) is a plant recently introduced in Cuba. Worldwide, it is an ethnomedicinal alternative for its use against microbial infections, but the Cuban population use the extracts to treat sleep disorders.
Annarli O. Rodríguez-Ferreiro +14 more
doaj +1 more source
Remimazolam (CNS 7056): an Emerging Sedative and General Anaesthetic [PDF]
Journal of Clinical and Diagnostic Research, 2018 Remimazolam is a newer drug in the field of anaesthesia. It combines the properties of midazolam and remifentanil. As the name indicates, midazolam is the parent compound of remimazolam which incorporates the pharmacokinetic properties of remifentanil ...
Sumit Bansal, Shubha Singhal
doaj +1 more source
Journal of Ayurveda, 2021 Background: Ayurvedic pharmacopoeia records vivid indications of Cannabis (Bhanga) including its analgesic, sedative and intoxicant actions. For inhibition of intoxication, Ayurveda recommends certain processing (Shodhana) techniques for Cannabis.
Swagata Dilip Tavhare +2 more
doaj +1 more source
Frontiers in Surgery, 2022 ObjectiveThe present study is designed to study the analgesic and sedative effect of different doses of dexmedetomidine combined with butorphanol in continuous analgesia after a cesarean section.MethodsA total of 60 puerperae undergoing a cesarean ...
Hui Liu +4 more
doaj +1 more source
Efficacy and Safety of Etomidate in Comparison with Propofol or Midazolam as Sedative for Upper Gastrointestinal Endoscopy [PDF]
Clinical Endoscopy, 2020 Background/Aims In this study, we compared the efficacy and safety of etomidate with those of propofol or midazolam for the maintenance of sedation during endoscopy. Methods The study enrolled patients who underwent sedative endoscopy in our hospital and
Jae Hyun Kim +8 more
doaj +1 more source
Proceedings of the 33rd international ACM SIGIR conference on Research and development in information retrieval, 2010 In recent years, active learning methods based on experimental design achieve state-of-the-art performance in text classification applications. Although these methods can exploit the distribution of unlabeled data and support batch selection, they cannot make use of labeled data which often carry useful information for active learning.
Yi Zhen, Dit-Yan Yeung
+6 more sources
High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]
, 2018 BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E. +12 more
core +1 more source
A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors [PDF]
, 2019 Alcohol produces both stimulant and sedative effects in humans and rodents. In humans, alcohol abuse disorder is associated with a higher stimulant and lower sedative responses to alcohol.
Bocarsly, Miriam E. +8 more
core +1 more source
Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor [PDF]
, 2020 In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR).
Belelli, Delia +3 more
core +1 more source
Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]
, 2016 AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F +7 more
core +1 more source