Comparison of Triple Combination Oral Sedation Regimens for Pediatric Dental Treatment [PDF]
, 2019 Purpose: Compare the efficacy of two benzodiazepines (diazepam or midazolam) in combination with meperidine and hydroxyzine for pediatric dental sedation.
Henderson, Brett H
core +1 more source
Effects of Patient-Directed Music Intervention on Anxiety and Sedative Exposure in Critically Ill Patients Receiving Mechanical Ventilatory Support: A Randomized Clinical Trial [PDF]
, 2013 Importance: Alternatives to sedative medications, such as music, may alleviate the anxiety associated with ventilatory support. Objective: To test whether listening to self-initiated patient-directed music (PDM) can reduce anxiety and sedative exposure ...
Chlan, Linda L. +6 more
core +3 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Zhongguo shipin weisheng zazhi, 2023 ObjectiveA simple and rapid method for the simultaneous determination of 7 kinds of fishery anesthetics and 2 kinds of sedatives in freshwater fish was developed using liquid chromatography tandem mass spectrometry （LC-MS/MS）.MethodsThe fish sample was ...
ZHOU Hua +4 more
doaj +1 more source
Effects of clown doctors on child and caregiver anxiety at the entrance to the surgery care unit and separation from caregivers [PDF]
, 2016 This study investigated the effects of hospital Clown Doctors intervention on child and caregiver preoperative anxiety at the entrance to the surgery care unit and separation from caregivers.
Arriaga, Patrícia, Pacheco, Catarina
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Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Вестник Северо-Кавказского федерального университета, 2022 The article reveals how when tested in open field was investigated range of activity (sedative, activating and anxiolytic effect) of biologically active compounds - derivatives of 4 - oxo - pyrimidine with acute and chronic administration of a dose 50 mg
Eleonora A. Manveljan +3 more
doaj
Desynchronization of pathological low-frequency brain activity by the hypnotic drug zolpidem. [PDF]
, 2008 Reports of the beneficial effects of the hypnotic imidazopyridine, zolpidem, described in persistent vegetative state^1, 2^ have been replicated recently in brain-injured and cognitively impaired patients^3-7^.
Alison E. Fisher +5 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Use of sedative drugs at reducing the side effects of voiding cystourethrography in children
Journal of Research in Medical Sciences, 2017 Background: Imaging of the kidneys and urinary tract has a significant and critical role for diagnosis of genitourinary system diseases. Although technological progress goes toward less invasive approaches, some of the current methods are still invasive ...
Anahita Alizadeh +5 more
doaj +1 more source