Results 111 to 120 of about 1,170,038 (344)

Anchored atomic Ru-O4 architecture enables ultra-effective Fe(VI) activation via avoiding Fe(VI) self-decay for water purification

open access: yesNature Communications
Ferrate (Fe(VI)) is a prospective green oxidant owing to producing highly reactive Fe(IV)/Fe(V) for micropollutant degradation. However, the performance is significantly compromised by the severe side reaction of Fe(VI) self-decay with H2O, generating ...
Yundan Chen   +4 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Sensitivity of fluvial sediment source apportionment to mixing model assumptions: A Bayesian model comparison [PDF]

open access: yes, 2014
Mixing models have become increasingly common tools for apportioning fluvial sediment load to various sediment sources across catchments using a wide variety of Bayesian and frequentist modeling approaches.
Aitchison   +66 more
core   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Paleogeographic numerical modeling of marginal seas for the Holocene – an exemplary study of the Baltic Sea [PDF]

open access: yesEarth System Dynamics
The sustainable management of marginal seas is based on a thorough understanding of their evolutionary trends in the past. The paleogeographic evolution of marginal seas is controlled not only by global and regional driving forces (eustatic sea-level ...
J. Miluch   +6 more
doaj   +1 more source

Sedimentation of microplastics interacting with sediment

open access: yes
The widespread presence of microplastics (MPs) in freshwater environments underscores the need to better understand their temporal and spatial dynamics. Investigating the settling velocity (W) of MPs in the water column is crucial for comprehending their transport mechanisms within river systems.
Mancini, Mirco   +4 more
openaire   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

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