Results 111 to 120 of about 1,803,074 (391)
High-resolution palynological analysis in Lake Sapanca as a tool to detect recent earthquakes on the North Anatolian Fault [PDF]
, 2009 High-resolution palynological analysis of a 38-cm-long core collected from Lake Sapanca, northwest Turkey, reveals large earthquakes that occurred during the second half of the 20th century along the North Anatolian Fault Zone. Four events have disturbed
Boyraz, S, Gürbüz, A, Leroy, SAG
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Past, present and future rainfall erosivity in central Europe based on convection-permitting climate simulations [PDF]
Hydrology and Earth System SciencesHeavy rainfall is the main driver of soil erosion by water, which is a threat to soil and water resources across the globe. As a consequence of climate change, precipitation – especially extreme precipitation – is increasing in a warmer world, leading to
M. Uber +4 more
doaj +1 more source
Medium-term performance and maintenance of SUDS:a case-study of Hopwood Park Motorway Service Area, UK [PDF]
, 2008 One of the main barriers to implementing SUDS is concern about performance and maintenance costs since there are few well-documented case-studies. This paper summarizes studies conducted between 2000 and 2008 of the performance and maintenance of four ...
Bray, R. +6 more
core +5 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Analytical Ultracentrifugation: Sedimentation Velocity and Sedimentation Equilibrium [PDF]
, 2008 Analytical ultracentrifugation (AUC) is a versatile and powerful method for the quantitative analysis of macromolecules in solution. AUC has broad applications for the study of biomacromolecules in a wide range of solvents and over a wide range of solute concentrations. Three optical systems are available for the analytical ultracentrifuge (absorbance,
Cole, James L. +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Nature CommunicationsFerrate (Fe(VI)) is a prospective green oxidant owing to producing highly reactive Fe(IV)/Fe(V) for micropollutant degradation. However, the performance is significantly compromised by the severe side reaction of Fe(VI) self-decay with H2O, generating ...
Yundan Chen +4 more
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source