Results 91 to 100 of about 3,735,810 (289)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Assessment of hydrology, sediment and particulate organic carbon yield in a large agricultural catchment using the SWAT model [PDF]

open access: yes, 2011
The Soil and Water Assessment Tool (SWAT, 2005) was used to simulate discharge and sediment transport at daily time steps within the intensively farmed Save catchment in south-west France (1110 km2).
Simeoni-Sauvage, Sabine   +6 more
core   +1 more source

Geoenvironmental Modeling of Mining Impacts in Southern Peru Using Sediment Fingerprinting

open access: yesMining
Identifying sediment sources in mining-impacted watersheds is essential for understanding sediment dynamics and supporting environmental management. This study applies a geoenvironmental modeling approach based on geochemical sediment fingerprinting to ...
Madeleine Guillen, Guillermo Iriarte
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Fingerprinting Suspended Sediment Sources in an Urbanized Watershed

open access: yes, 2018
The elevated supply of fine-grained sediment to a river system negatively impacts the water quality and ecosystem health. Therefore, quantification of the relative contribution from different sources to in-stream sediment is of major interest to target ...
Jasmeet Lamba   +3 more
core   +1 more source

Seasonal Variation of Acid Volatile Sulfide and Simultaneously Extracted Metals in Sediment Cores from the Pearl River Estuary [PDF]

open access: yes, 2014
The simultaneously extracted metals/acid volatile sulfide (SEM/AVS) method is widely used to estimate the toxicity of metals in sediment. In this study, SEM and AVS concentrations were obtained by the cold-acid purge-and-trap technique during spring ...
Chen, Fanrong   +11 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Dynamics of suspended sediment transport and yield in a large agricultural catchment, southwest France [PDF]

open access: yes, 2010
The dynamics of suspended sediment transport were monitored continuously in a large agricultural catchment in southwest France from January 2007 to March 2009.
Simeoni-Sauvage, Sabine   +3 more
core   +1 more source

Determining Sediment Contribution of Land Use Units in Kond Watershed using the Fingerprinting Approach

open access: yesعلوم آب و خاک, 2017
Obtaining information about relative importance of sediment sources and their contributions on sediment production and thus identification of on-site critical areas is required for implementing soil and water conservations and sediment control programs ...
M. Zarea Khormizi   +3 more
doaj  

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