Results 41 to 50 of about 3,735,810 (289)

Composite Fingerprint Analysis of Sediment Sources in a Watershed Disturbed by Road Construction in Southeastern Tibet

open access: yesLand
Construction activities such as road projects modify original land uses and intensify soil erosion. Understanding the sediment contributed by these projects and its spatial variation throughout a watershed is critical in terms of guiding conservation ...
Xin Li   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Sediment budget for a North Pennine upland reservoir catchment, UK [PDF]

open access: yes, 2003
Sediment delivery from upland fluvial systems in the UK is of considerable importance in catchment management. However, scarcity of detailed data on sediment sources, storage and linkages between geomorphic processes inhibits current understanding of ...
Holliday, Victoria Jane
core  

APPLICABILITY OF FINGERPRINTING FOR IDENTIFICATION OF SEDIMENT SOURCES IN A MESOSCALE SEMIARID CATCHMENT [PDF]

open access: yesEngenharia Agrícola, 2018
The study aimed at identifying sediment sources in a mesoscale catchment (933 km2) located in the Brazilian semiarid region. The research explored the potential of using a fingerprinting technique to verify the origin of eroded sediments in a catchment ...
Eveline M. R. da Silva   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Sources and impacts of inorganic and organic fine sediment in salmonid spawning gravels in chalk rivers

open access: yes, 2012
Poor salmonid spawning habitat due to excessive fine sediment inputs has been identified as a major factor limiting survival in chalk rivers. A lack of knowledge about the complex processes and factors affecting survival was the driver for this study and
Bateman, Samantha
core   +1 more source

A GIS-based multiscale mapping framework to assess and visualize complex and polygenetic geomorphic systems – A novel ‘Geomorphic Entities’ approach

open access: yesJournal of Maps
This paper presents a novel GIS-based methodological framework for multiscale digital mapping and database implementation in sediment dynamics assessments.
Manuel La Licata   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Coupling Climate Conditions, Sediment Sources and Sediment Transport in an Alpine Basin [PDF]

open access: yesLand Degradation & Development, 2017
AbstractIn a fluvial system, mountain basins control sediment export to the lowland rivers. Hence, analysis of erosion processes and sediment delivery patterns in mountain basins is a key factor for many applications such as land‐use management, hazard assessment and infrastructure design.
Riccardo Rainato   +5 more
openaire   +7 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy