Results 41 to 50 of about 3,735,810 (289)
Construction activities such as road projects modify original land uses and intensify soil erosion. Understanding the sediment contributed by these projects and its spatial variation throughout a watershed is critical in terms of guiding conservation ...
Xin Li +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Sediment budget for a North Pennine upland reservoir catchment, UK [PDF]
Sediment delivery from upland fluvial systems in the UK is of considerable importance in catchment management. However, scarcity of detailed data on sediment sources, storage and linkages between geomorphic processes inhibits current understanding of ...
Holliday, Victoria Jane
core
APPLICABILITY OF FINGERPRINTING FOR IDENTIFICATION OF SEDIMENT SOURCES IN A MESOSCALE SEMIARID CATCHMENT [PDF]
The study aimed at identifying sediment sources in a mesoscale catchment (933 km2) located in the Brazilian semiarid region. The research explored the potential of using a fingerprinting technique to verify the origin of eroded sediments in a catchment ...
Eveline M. R. da Silva +2 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Poor salmonid spawning habitat due to excessive fine sediment inputs has been identified as a major factor limiting survival in chalk rivers. A lack of knowledge about the complex processes and factors affecting survival was the driver for this study and
Bateman, Samantha
core +1 more source
This paper presents a novel GIS-based methodological framework for multiscale digital mapping and database implementation in sediment dynamics assessments.
Manuel La Licata +4 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Coupling Climate Conditions, Sediment Sources and Sediment Transport in an Alpine Basin [PDF]
AbstractIn a fluvial system, mountain basins control sediment export to the lowland rivers. Hence, analysis of erosion processes and sediment delivery patterns in mountain basins is a key factor for many applications such as land‐use management, hazard assessment and infrastructure design.
Riccardo Rainato +5 more
openaire +7 more sources
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

