Results 41 to 50 of about 174,490 (303)

Mangarara Formation: exhumed remnants of a middle Miocene, temperate carbonate, submarine channel-fan system on the eastern margin of Taranaki Basin, New Zealand [PDF]

, 2009
The middle Miocene Mangarara Formation is a thin (1–60 m), laterally discontinuous unit of moderately to highly calcareous (40–90%) facies of sandy to pure limestone, bioclastic sandstone, and conglomerate that crops out in a few valleys in North ...
Armstrong BD, Betzler C, Beu AG, Gani MR, Harris D, Harris D, Hay RF, Hayward BW, Hornibrook N, Hornibrook N, Hunt D, Hunt TM, Lowe DR, Lowe DR, Martin JM, Nelson CS, Nodder SD, Piper DJW, Posamentier HW, Puga‐Bernabéu A, Reading HG, Ricketts BD, Ruíz‐Ortíz PA, Shanmugam G, Stagpoole V, Wright VP   +25 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Applying the water quality indices and geographic information system approach to assessing the suitability of groundwater quality for drinking and irrigation purposes in the semi-arid region of Tebessa-Ain Chabro, Northeastern Algeria

Applied Water Science
Assessing the groundwater quality is important for the efficient exploitation of water resources in semi-arid areas. The study area in northeast Algeria mostly depends on groundwater as its main source of water, and the quality of groundwater is becoming
Messaoud Abidi Saad, Karima Seghir, Abdeldjebar Touahri, Mehdi Bendekkoum, Abdelaziz Bellaoueur   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Spatio-temporal evolution of intraplate strike-slip faulting: the Neogene-Quaternary Kuh-e-Faghan Fault, Central Iran [PDF]

, 2016
Central Iran provides an ideal region to study the long-term morphotectonic response to the nucleation and propagation of intraplate faulting. In this study, a multidisciplinary approach that integrates structural and stratigraphic field investigations ...
Berberian, Claudio Faccenna, Cox, Domenico Cosentino, Dooley, Federico Rossetti, Finlay M. Stuart, Fossen, Gabriele Calzolari, Gianluca Vignaroli, Hafkenscheid, Hollingsworth, Homke, Jackson, Khadivi, Maria Laura Balestrieri, Marta Della Seta, Molnar, Raimondo, Reilinger, Reza Nozaem, Sella, Simons, Spotila, Valerio Olivetti   +24 more
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A comprehensive procedure for pollen extraction from bat guano deposits in organic and detrital matrices

MethodsX, 2023
Although bat guano deposits have been proven to be excellent environmental archives for paleoecological and paleoclimate studies, the development of a standardized method specially catering to pollen extraction has received no attention so far.
Luiza Santos Reis, Paulo Eduardo de Oliveira, Qiang Yao   +2 more
doaj   +1 more source

Recent high-energy marine events in the sediments of the Lagoa de Óbidos and Martinhal (Portugal): Recognition, age and likely causes [PDF]

, 2012
© 2012 Author(s) - This work is distributed under the Creative Commons Attribution 3.0 License.This article has been made available through the Brunel Open Access Publishing Fund.A key issue in coastal hazards research is the need to distinguish ...
Costa, PJM, Dawson, AG, Dinis, JL, Kortekaas, S, Leroy, SAG   +4 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source