Results 51 to 60 of about 6,281,017 (289)

Tight regulation of Earth’s long-term temperature over Phanerozoic time

Nature Communications
Knowing the past temperature of the Earth is crucial for understanding the mechanisms driving climate change and biosphere evolution, but there is significant debate about the range of past temperature variation.
Dongyu Zheng, Alex G. Lipp, Alexander Farnsworth, Shufeng Li, Andrew S. Merdith, Khushboo Gurung, Mingcai Hou, Anqing Chen, Zixi Hou, Daniel J. Lunt, Erik A. Sperling, Paul J. Valdes, Benjamin J. W. Mills   +12 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Reconstructing a continuous Holocene composite sedimentary record for the eastern Gotland Deep, Baltic Sea

, 2002
It has been generally assumed that sediments in the deepest parts of the Gotland Basin have accumulated in a relatively calm depositional environment during the entire Holocene, thus representing a continuous sedimentary record. As part of the Baltic Sea
Kotilainen, A.T., Hämäläinen, J.M.S., Winterhalter, B.   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

3. Sedimentary rocks

, 2016
The Earth has the greatest abundance and variety of sedimentary strata in our star system, dating back some 3.8 billion years. ‘Sedimentary rocks’ describes the processes that create different types of sedimentary rocks, which form a key guideline in ...
Jan Zalasiewicz
core   +1 more source

Research on the Sedimentary and Paleoclimate Environment of the Xiaoheba Formation in Southeastern Sichuan Based on the Trace Elements Ratio Method

Yankuang ceshi, 2017
Lower Silurian sandstone of the Xiaoheba formation in Southeastern Sichuan has a good reservoir seal combination, and an oil and gas geological condition, but the hypothesis that the sedimentary environment belongs to continental or marine sedimentary ...
YANG Hai-ou, WANG Chang-cheng, LI Wen-jie, DONG Hua, GONG Xiao-xing   +4 more
doaj   +1 more source

Distribution of Trace Elements, Sr-C Isotopes, and Sedimentary Characteristics as Paleoenvironmental Indicator of the Late Permian Linxi Formation in the Linxi Area, Eastern Inner Mongolia

Journal of Chemistry, 2020
The Late Permian on the periphery of the Songliao Basin, eastern Inner Mongolia, is an important hydrocarbon source rock system. Its sedimentary environment plays an important role in the evaluation of hydrocarbon prospects in the area.
Linlin Wang, Yongsheng Zhang, Enyuan Xing, Yuan Peng, Dongdong Yu   +4 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source