Results 51 to 60 of about 7,029,640 (338)

Overwash sedimentary dynamics in the Ria Formosa barrier islands [PDF]

, 2006
Tese dout., Ciências do Mar, Universidade do Algarve ...
Matias, Ana
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Pliocene-Pleistocene marine cyclothems, Wanganui Basin, New Zealand: a lithostratigraphic framework [PDF]

, 1995
The Rangitikei River valley between Mangaweka and Vinegar Hill and the surrounding Ohingaiti region in eastern Wanganui Basin contains a late Pliocene to early Pleistocene (c. 2.6-1.7 Ma), c.
Abbott S. T., Aguirre E., Anderton P. W., Feldmeyer A. E., Fleming C. A., Milne J. D. G., Naish T. R., Pillans B., Seward D., Shackleton N. J., Stern T. A., Te Punga M. T., Vail P., Wilson G. S.   +13 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

The role of the sedimentary regime in shaping the distribution of subtidal sandbank environments and the associated meiofaunal nematode communities: an example from the southern North Sea. [PDF]

PLoS ONE, 2014
We combined sediment and faunal data to explore the role of the sedimentary regime in shaping the distribution of subtidal sandbank environments and the associated meiofaunal nematode communities at Broken Bank and Swarte Bank, in the southern North Sea.
Michaela Schratzberger, Piers Larcombe
doaj   +1 more source

Palaeoenvironmental and diagenetic reconstruction of a closed-lacustrine carbonate system - the challenging marginal setting of the Miocene Ries Crater Lake (Germany) [PDF]

, 2017
Chemostratigraphic studies on lacustrine sedimentary sequences provide essential insights on past cyclic climatic events, on their repetition and prediction through time.
Abdul Aziz, Allan, Allan, Alonso-Zarza, Anadon, Anadón, Anderson, Andrews, Arp, Arp, Arp, Arp, Barnaby, Beier, Benito, Bennett, Brand, Buchner, Buchner, Budd, Böhme, Böhme, Börner, Chamberlain, Christ, Christ, Danielopol, Decrouy, Depeche, Dickson, Dravis, Dwyer, Einsele, Emrich, Flügel, Gentner, Gierlowski-Kordesch, Godet, Goldstein, Gouramanis, Grafenstein, Gray, Halley, Hays, Heaton, Holmes, Immenhauser, Immenhauser, Jankowski, Janz, Janz, Joachimski, Junge, Keatings, Kontrovitz, Kooij, Kwiecien, Leng, Leng, Li, Li, Lohmann, Lohmann, Mangili, Mangili, Marshall, Marshall, Mayr, Mazzini, Melezhik, Mischke, Mutti, Niemann, Oehlerich, Orszag-Sperber, Pache, Pohl, Prieto, Richter, Richter, Riding, Romanek, Rothe, Sanz, Schwarz, Sheppard, Stansell, Staudacher, Stevens, Swart, Talbot, Tütken, Vasconcelos, Wilson, Wittkop, Xia   +95 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Dispersion, Accumulation, and the Ultimate Fate of Microplastics in Deep-Marine Environments: A Review and Future Directions

Frontiers in Earth Science, 2019
An estimated 8.3 billion tonnes of non-biodegradable plastic has been produced over the last 65 years. Much of this is not recycled or disposed of ‘properly’, has a long environmental residence time and accumulates in sedimentary systems worldwide ...
I. Kane, M. Clare
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Grain Shape Variation of Different Sand-Sized Particles and Its Implication for Discriminating Sedimentary Environment

Geosciences
Particle shape analysis is essential in sedimentological research, as it offers vital insights into the sedimentary environment and transport history. However, little is known about the particle shape variation across different sand fractions, as well as
Fangen Hu, Xia Xiao
doaj   +1 more source