Results 41 to 50 of about 175,945 (263)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Influence of temperature and ion concentration on sedimentation characteristics of Tricalcium phosphate (TCP) and Tristrontium phosphate (TSP) Precipitates

Journal of Applied Sciences and Environmental Management, 2018
Physical and chemical variables of insoluble salts generally affect sedimentation characteristics of precipitates. In this research study, the effects of temperature and ion concentration on the sedimentation of tricalcium phosphate (TCP) and ...
C.C. Obunwo, S.D. Iboroma, G.A. Cookey
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

ANALYSIS OF PROBABLE MECHANISM OF PARTIAL METAL MELT STRATIFICATION IN CAPILLARS [PDF]

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2013
Review of experiments on stratification of binary metal melts in capillaries has been performed. Considering old results and new experimental data represented in this paper, conclusion has made that effect of the layering can be explained only with ...
N.P. Ouglev
doaj  

Velocidade de hemossedimentação: comparação entre o método Microtest X (microssedimentação) e o método de referência Westergren Erythrocyte sedimentation rate: comparison between the Microtest X technique (micro-sedimentation) and the Westergren reference method

Revista Brasileira de Hematologia e Hemoterapia, 2009
The erythrocyte sedimentation rate (ESR) is an easy and common routine laboratory technique. Over the last few decades, new methods have been proposed to reduce biological sample manipulation, to measure rates using an automated system, to optimize the ...
Anna L. Soares, Elcivane A. Santos
doaj   +1 more source

Clinical efficacy of teicoplanin combined with L-carnitine for methicillin-resistant Staphylococcus aureus infective endocarditis

Di-san junyi daxue xuebao, 2020
Objective To observe the clinical efficacy of teicoplanin combined with levocarnitine in treatment of methicillin-resistant Staphylococcus aureus (MRSA) infective endocarditis (IE). Methods A total of 84 patients diagnosed with IE caused by MRSA admitted
JIANG Ximeng, TIAN Donghua, WANG Xiaoli, ZHANG Jinying   +3 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Modelling mass accumulation rates and 210Pb rain rates in the Skagerrak: lateral sediment transport dominates the sediment input

Frontiers in Marine Science
Sediment fluxes to the seafloor govern the fate of elements and compounds in the ocean and serve as a prerequisite for research on elemental cycling, benthic processes and sediment management strategies.
Timo Spiegel, Markus Diesing, Andrew W. Dale, Nina Lenz, Mark Schmidt, Stefan Sommer, Christoph Böttner, Michael Fuhr, Habeeb Thanveer Kalapurakkal, Cosima-S. Schulze, Klaus Wallmann   +10 more
doaj   +1 more source

Effect of sodium carboxymethylcellulose biopolymer on sedimentation properties of trimagnesium, tricalcium and tristrontium phosphates precipitates

Journal of Applied Sciences and Environmental Management, 2018
Sedimentation data of bioactive materials are essential in formulation of suspension with desirable requirements. Batch-wise precipitation and sedimentation tests were conducted to evaluate the effect of sodium carboxymethylcellulose (Na-CMC) biopolymer
S.D. Iboroma, G.A. Cookey, C.C. Obunwo
doaj   +1 more source