Results 71 to 80 of about 175,945 (263)
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Sediment Depositional History and Processes for the Eurasian Basin Since 54 Ma, Arctic Ocean
Geochemistry, Geophysics, GeosystemsThe Eurasian Basin in the Arctic Ocean, comprising the Amundsen and Nansen Basins separated by the Gakkel Ridge, has sediment deposits up to 4–5 km thick. However, its sedimentation history and processes remain poorly understood.
Pingchuan Tan +3 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
MagnetochemistryMagnetorheological fluids (MRFs) are widely used for various kinds of controllable devices since their properties can be controlled by an external magnetic field.
Elliza Tri Maharani +4 more
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Журнал Белорусского государственного университета: Химия, 2017 The effect of aluminium coagulants composition on colloidal characteristics of humic substances dispersions (diameter, particle size distribution, density and sedimentation rate of aggregates) was investigated by using of laser diffraction method ...
Alesia V. Zyhmant +3 more
doaj
All EarthLake sediments record the environment during the lake sedimentation whose characteristics can infer environmental changes and human activities. In this study, the 210Pb chronologies and sedimentation rate of the sediment core in Honghu Lake were ...
Mingli Zhang +3 more
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Frontiers in Earth ScienceSedimentation tank design is of key importance in a water diversion project. Both physical and numerical models are used to study the hydrodynamics and sediment transport in the sedimentation tank of the Oujiang Water Diversion Project.
Jian Chen +6 more
doaj +1 more source