Results 71 to 80 of about 3,925,714 (336)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Stabilization of Dredged Marine Sediment Using Biopolymer [PDF]

The frequent dredging of sediments from port areas often leads to the rapid accumulation of excess material, potentially resulting in landfill challenges. Dredged marine sediments typically exhibit high water content, a significant proportion of fine-grained soil, limited bearing capacity, substantial settlement tendencies, and low shear strength ...
Ghafoori, Yaser, Samadi, Parisa, Ghadir, Pooria, Lenart, Stanislav, Dolenec, Sabina, Khodadadi Tirkolae, Hamed   +5 more
openaire   +1 more source

Stabilization and recycling of contaminated marine sediments [PDF]

E3S Web of Conferences, 2019
The paper deals with the treatment and reuse of submarine sediments, i.e. a relevant environmental issue due to the annual huge quantities of dredged sediments (over half contaminated) in Europe. In a vision of sustainability and circular economy, stabilization and solidification (S/S) treatments represent an interesting solution for both environmental
Francesco Todaro, Claudia Vitone, Michele Notarnicola   +2 more
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study on the tribological and rheological properties of magnetorheological fluids based on different base oils

Materials Research Express
Base oil has great influence on the tribological and rheological properties of magnetorheological fluid. In this paper, four types of magnetorheological fluid are prepared respectively by silicone oil, mineral oil, synthetic oil (PAO) and castor oil, and
Long Yu, Fei Chen, Hao-Peng Li
doaj   +1 more source

Capture of particles of dust by convective flow

, 2006
Interaction of particles of dust with vortex convective flows is under theoretical consideration. It is assumed that the volume fraction of solid phase is small, variations of density due to nonuniform distribution of particles and those caused by ...
Arthur V. Straube, Dementiev O., Dement’ev O. N., Dmitry V. Lyubimov, Gershuni G. Z., Lyubimov D. V., Mordant N., Nayfeh A. H., Nigmatulin R. I., Ottino J. M., Schwabe D., Soo S. L., Squire H. B., Stommel H., Tatyana P. Lyubimova, Williams F. A.   +15 more
core   +1 more source

Sedimentation and Flow Through Porous Media: Simulating Dynamically Coupled Discrete and Continuum Phases [PDF]

, 1995
We describe a method to address efficiently problems of two-phase flow in the regime of low particle Reynolds number and negligible Brownian motion. One of the phases is an incompressible continuous fluid and the other a discrete particulate phase which ...
A. J. C. Ladd, A. J. Chorin, A. J. Chorin, A. J. Goldman, A. L. Fogelson, A. Ladd, A. Ladd, B. Cichocki, B. E. Launder, D. L. Koch, E. J. Hinch, E. J. Hinch, F. A. L. Dullien, F. Feuillebois, G. K. Batchelor, G. K. Batchelor, G. Ristow, H. C. Brinkman, H. Kopetsch, H. Nicolai, H. Nicolai, I. Goldhirsch, J. F. Brady, J. F. Richardson, J. Feng, J. Happel, J. Z. Xue, K. Ichiki, M. P. Allen, M. R. Maxey, O. R. Walton, P. A. Cundall, R. E. Caflisch, R. H. Davis, R. Jackson, R. Peyret, S. Childress, S. Ergun, S. Ergun, S. L. Soo, S. McNamara, S. V. Patankar, S. Yonemura, Stefan Schwarzer, Y. Tsuji   +44 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A review on the stability of magnetorheological materials

Manufacturing Review
Magnetorheological materials, as a type of intelligent controllable material, have broad application prospects in the engineering field. However, stability issues (such as sedimentation, particle agglomeration, and extreme temperature adaptability ...
Sang Yuanyuan, Feng Yongbao, Han Xiaoxia, Huang Zhen, Li Liang, Wang Xinfeng   +5 more
doaj   +1 more source