Results 111 to 120 of about 724,210 (314)

Metazoans of redoxcline sediments in Mediterranean deep-sea hypersaline anoxic basins [PDF]

open access: yes, 2015
Background: The deep-sea hypersaline anoxic basins (DHABs) of the Mediterranean (water depth similar to 3500 m) are some of the most extreme oceanic habitats known.
Beaudoin, David J   +7 more
core   +4 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Espècie nova del gènere Moitessieria (Gastropoda: Moitessieriidae) per a Catalunya, Espanya [PDF]

open access: yes, 2019
A new species of the genus Moitessieria Bourguignat, 1863 from Catalonia (Spain) is described, found in sediments from a spring in Sant Joan les Fonts (Girona).
Quiñonero Salgado, Sergio   +1 more
core  

Biostratigraphic and magnetostratigraphic synthesis of the Celebes and Sulu Seas, Leg 124 [PDF]

open access: yes, 1991
During ODP Leg 124, late middle Eocene to Quaternary sediment sequences were recovered from 13 holes drilled at five sites in the Celebes and Sulu basins. Paleomagnetic measurements and biostratigraphic studies using calcareous nannofossils, planktonic
Hsu, V.   +7 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Contaminated Aquatic Sediments [PDF]

open access: yesWater Environment Research, 2007
A review of the literature published in 2014 relating to the assessment, evaluation and remediation of contaminated aquatic sediments is presented. The review is divided into the following sections: policy and guidance, methodology, distribution, fate and transport, bioavailability, bioaccumulation, risk, toxicity and remediation.
openaire   +9 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Effects of macrobenthos on sediment-water oxygen and ammonium fluxes. Final Report. [PDF]

open access: yes, 1997
Sediments are an important location in determining the fate of nutrients entering the estuary. Role of sediments needs to be incorporated into water quality models.
Barnes, J.M.   +3 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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