Results 121 to 130 of about 724,210 (314)

Sources and mechanisms for the enrichment of highly reactive iron in euxinic Black Sea sediments [PDF]

open access: yes, 2004
The deep basinal euxinic sediments of the Black Sea are enriched in iron that is highly susceptible to sulfidization compared to oxic/suboxic continental margin sediments in the Black Sea and oxic/dysoxic continental margin and deep-sea sediments ...
Anderson, T.F., Raiswell, R.
core  

First Results of a Campaign of the Measurement of Polycyclic Aromatic Hydrocarbons in the Sediments of the Hooghly River, West Bengal, India

open access: yesJournal of Marine Science and Engineering
This study presents the first data on a 2018–2021 campaign to monitor polycyclic aromatic hydrocarbon levels, PAHs, in the final stretch of the Hooghly River in West Bengal, India.
Michele Arienzo   +8 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Levels and sources of PCDDs, PCDFs and dl-PCBs in the water ecosystems of central Poland — A mini review

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2014
Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) are unwanted by-products in a variety of industrial and thermal processes. They have been present on Earth long before the human era, since they may be also formed as a result of forest ...
Marek Zieliński   +4 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Microbial diversity in Baltic Sea sediments [PDF]

open access: yes, 2007
This thesis focuses on microbial community structures and their functions in Baltic Sea sediments. First we investigated the distribution of archaea and bacteria in Baltic Sea sediments along a eutrophication gradient.
Edlund, Anna
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

The influence of xenobiotics in river sediment on the reproduction and survival of Daphnia magna, 1820, Straus Influência de xenobióticos no sedimento de rio sobre a reprodução e a sobrevivência de Daphnia magna, 1820, Straus

open access: yesActa Limnologica Brasiliensia, 2012
AIM: The Taquari River, a tributary of Guaíba Lake, is a major economic and environmental source for Rio Grande do Sul, a state located in the far south of Brazil; METHODS: This study evaluated the interference of sediment from this river in the ...
Silvana Pereira Gonçalves   +3 more
doaj  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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