Results 71 to 80 of about 1,363,325 (344)

Butyltin compounds in a sediment core from the old Tilbury basin, London, UK [PDF]

, 2005
Sections from a sediment core taken from the River Thames were analysed for butyltin species using gas chromatography with species-specific isotope dilution mass spectrometry.
Almeida, Alzieu, Alzieu, Appleby, Bartlett, Batley, Bennett, Berg, Bhosle, Blunden, Booty, Broodbank, Burton, Chiron, Clark, Cundy, Dahllof, de Mora, Dowson, Dowson, Dowson, Dowson, Evans, Fent, Fent, Fernandez, Greeves, Harino, Hoch, Horiguchi, IMO, J.N. Lester, Jones, M.D. Scrimshaw, Midorikawa, R. Wahlen, Ramaswamy, Randall, Rodriguez-Gonzalez, Sarradin, Scrimshaw, Smith, Sturgeon, Sturgeon, Sudaryanto, T. Catterick, Thomas, Unger, Viglino, Voulvoulis, Voulvoulis, Wahlen, Wiese   +52 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Deep Sea Sedimentation

Environmental Health Perspectives, 1974
An important problem in the study of microparticles in the marine environment, suspended in the water column or deposited as sediment on the ocean bottom, is the determination of provenance of the microparticles-where did they come from and by what processes were they transported to the sampling location?
openaire   +2 more sources

Spatial and temporal trends of iron and iron isotope cycling in the Peruvian oxygen minimum zone [PDF]

, 2012
Iron (Fe) is a key element in the global ocean’s biogeochemical framework because of its essential role in numerous biological processes. A poorly studied link in the oceanic Fe cycle is the reductive release of Fe from sediments in oxygen depleted ocean
Haley, Brian, Hensen, Christian, McManus, James, Noffke, Anna, Schneider, Ralph, Scholz, Florian, Severmann, Silke, Wallmann, Klaus   +7 more
core  

Effects of the Invasive Freshwater Mussel Limnoperna fortunei on Sediment Properties and Accumulation Rates [PDF]

, 2018
Since its introduction into South America around 1990, the freshwater bivalve Limnoperna fortunei (the golden mussel) has spread rapidly and is now a dominant component of the benthic and periphytic fauna in many rivers, lakes, and reservoirs.
Barbosa, Bazan, Bertness, Biswas, Bloesch, Boltovskoy, Boltovskoy, Boltovskoy, Boltovskoy, Bonachea, Boyd, Burlakova, Carlsson, Cataldo, Cataldo, Chaffin, Cicchetti, Colombo, Crawford, Depetris, Di Gregorio, Dillon, Framiñan, Gergs, Graf, Grenz, Hammer, Hartstein, Hatcher, Hoogsteen, Horppila, Jørgensen, Karatayev, Karatayev, Karatayev, Kaspar, Kleeberg, Klerks, Li, Linares, MacIsaac, Mayer, Mazouni, McCall, Mellina, Mida, Moreira, Moreira, Mosley, Musin, Nalepa, Newell, Newell, Oliveira, Ozersky, Reeders, Reynolds, Roditi, Ronco, Ruginis, Sardiña, Sardiña, Schuerch, Smyth, Sobczyński, Sornin, Sprung, Strayer, Sylvester, Sylvester, Sylvester, Sylvester, Tokumon, Torres, Tye, Valderrama, Vanderploeg, Wetzel, Yamada, Zaiko   +79 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Assessing the effects of model parameter assumptions on surface-wave inversion resultsKey points

Earthquake Science
Surface-wave inversion is a powerful tool for revealing the Earth’s internal structure. However, aside from shear-wave velocity (vS), other parameters can influence the inversion outcomes, yet these have not been systematically discussed.
Xuezhen Zhang, Xiaodong Song
doaj   +1 more source

Lithology and palynology of cave floor sediment cores from Wakulla Spring, Wakulla County, Florida [PDF]

, 1991
Five short bottom sediment cores taken in Wakulla Spring Wakulla County, Florida, were described lithologically and sampled for palynological study. Four of the cores were recoveredfrom sediments at the spring cave entrance (130 feet water depth).
Rupert, Frank R.
core  

Influence of hydrodynamic processes on the fate of sedimentary organic matter on continental margins [PDF]

, 2018
Understanding the effects of hydrodynamic forcing on organic matter (OM) composition is important for assessment of organic carbon (OC) burial in marginal seas on regional and global scales.
Aller, Aller, Arnarson, Bao, Bao, Bauer, Bianchi, Bianchi, Bianchi, Blair, Blair, Blair, Bröder, Burdige, Burdige, Cameron McIntyre, Canuel, Cartapanis, Cathalot, Chen, Coppola, Cui, Daniel B. Montluçon, Drenzek, Eglinton, Galy, Gao, Goñi, Griffith, Guo, Harris, Hedges, Hilton, Hilton, Hwang, Inthorn, Kao, Keil, Keil, Kusch, Kusch, Leithold, Li, Lie, Liu, Liu, Liu, Liu, Luo, Marwick, Mayer, McCave, McCave, McCave, Meixun Zhao, Milliman, Mollenhauer, Mollenhauer, Mollenhauer, Mollenhauer, Mollenhauer, Mollenhauer, Muller-Karger, Nuwer, Ohkouchi, Pawlowicz, Pedrosa-Pàmies, Qiao, Rui Bao, Saito, Shah, Stuiver, Su, Tao, Tao, Tesi, Tesi, Tesi, Tesi, Tessa S. van der Voort, Thomsen, Thomsen, Timothy I. Eglinton, Voort, Wagner, Wakeham, Wang, Wang, Wang, Wang, Wang, Wang, Wu, Xinyu Guo, Xu, Yang, Yang, Yang, Yang, Yao, Yao, Zhu, Zonneveld   +102 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source