Results 61 to 70 of about 719,062 (315)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Analysis of the synchronous rise of water level in the Tangshan fault zone

Scientific Reports
Since 2019, a synchronous and abnormal upward trend in water levels has been observed in the Tangshan and Majiagou observation wells, located within the Tangshan fault zone, coinciding with three earthquakes of magnitude 4.0 or higher in the Tangshan ...
Jie Tang, Suxin Zhang, Dong Ma, Yan Wang, Lina Sun, Wenlou Luan   +5 more
doaj   +1 more source

INFLUENCE FISH FARMING IN TANKS ON STRUCTURAL AND FUNCTIONAL CHARACTERISTICS AND ACCUMULATION OF SEDIMENTS IN THE BASIN-COOLER

Ribogospodarsʹka Nauka Ukraïni, 2013
Purpose. Establishing change the basic structural and functional characteristics of the sediments under the influence of waste going fish farming in tanks. Methodology. Bottom sediment samples were collected using a 1 m of dirt tube (SOI-1), according
N. Starkо
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

The Terrestrialization of Amphibious Life in a Danube Delta 'Town on Water'

Suomen Antropologi, 2019
The Danube Delta town of Vilkovo is often called the ‘Ukrainian Venice’ because of its 40 kilometers of canals. Many of these canals, however, are rapidly filling in with silt and are often impassible by boat.
Tanya Richardson
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Tool4S: A GUI-based python software tool for seismic station site selection data processing and analysis

SoftwareX
Data quality is the foundation of further research. It’s essential to find a seismic station whose data could be collected without being significantly affected by surrounding noise sources.
Cheng Ding, Chengli Jiao, Shuang Zheng, Zhiyuan Zhao, Xiangdong Feng   +4 more
doaj   +1 more source

Metazoans of redoxcline sediments in Mediterranean deep-sea hypersaline anoxic basins [PDF]

, 2015
Background: The deep-sea hypersaline anoxic basins (DHABs) of the Mediterranean (water depth similar to 3500 m) are some of the most extreme oceanic habitats known.
Beaudoin, David J, Bernhard, Joan M, Edgcomb, Virginia P, Kormas, Konstantinos Ar, Morrison, Colin R, Pachiadaki, Maria G, Pape, Ellen, Todaro, M Antonio   +7 more
core   +4 more sources

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source