Results 71 to 80 of about 719,062 (315)

Anoxic nitrification in marine sediments [PDF]

, 2004
Nitrate peaks are found in pore-water profiles in marine sediments at depths considerably below the conventional zone of oxic nitrification. These have been interpreted to represent nonsteady- state effects produced by the activity of nitrifying ...
Anschutz, P., Barnes, J., Davies, I.M., Freitag, T.E., Harris, S.J., Hayes, P.J., Krom, M.D., Mortimer, R.J.G., Prosser, J.I.   +8 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Numerical modeling of underwater parametric propagation to detect buried objects [PDF]

, 2011
In underwater acoustics, detection of buried objects in sediments (cables, mines,…) is a complex problem. One reason is that acoustic attenuation in these sediments increases with frequency. To ensure sufficient penetration depth in marine sediments, low
BOU MATAR, Olivier, BOUTTARD, Etienne, LABAT, Valérie   +2 more
core   +1 more source

Deep Sea Sedimentation

Environmental Health Perspectives, 1974
An important problem in the study of microparticles in the marine environment, suspended in the water column or deposited as sediment on the ocean bottom, is the determination of provenance of the microparticles-where did they come from and by what processes were they transported to the sampling location?
openaire   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Assessing the effects of model parameter assumptions on surface-wave inversion resultsKey points

Earthquake Science
Surface-wave inversion is a powerful tool for revealing the Earth’s internal structure. However, aside from shear-wave velocity (vS), other parameters can influence the inversion outcomes, yet these have not been systematically discussed.
Xuezhen Zhang, Xiaodong Song
doaj   +1 more source

Evaluating the influence of lake morphology, trophic status and diagenesis on geochemical profiles in lake sediments [PDF]

, 2010
Recent geochemical studies provide evidence that changes in vertical distributions of nutrients in lake sediments are driven by anthropogenic activities, based primarily on trends of increasing concentrations in upper sediment layers.
Hamilton, David P., Pilditch, Conrad A., Trolle, Dennis   +2 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Type Specimens of the Species of the Genus Papillicalymene (Arthropoda, Trilobita) from Ukraine Described by Leonid Konstantynenko

Zoodiversity
The article presents diagnoses and information on the type series of two trilobite species of the genus Papillicalymene Shirley, 1936: P. dnistroviana Konstantynenko, 2006 and P. sokoliana Konstantynenko, 2006 from the Ludlow (Upper Silurian) of Podillia
V. Dernov
doaj   +1 more source