Results 121 to 130 of about 155,966 (283)

Farm-economics of genetically improved carp strains in major Asian countries and carp seed price policy model [PDF]

open access: yes
The study has conducted the micro level analysis of hatchery operators, fishseed-rearing farmers and carp farmers with respect to their socio-economic characteristics, infrastructural development, husbandry practices and economics returns, based on the ...
Barik, Nagesh K.   +2 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

ALFALFA SEED GROWING AND THE WEATHER, IN UTAH

open access: yesMonthly Weather Review, 1919
Abstract SYNOPSIS The first crop of alfalfa is usually cut for hay in Utah, and the second crop is allowed to go to seed. The seed crop should have sufficient moisture during its early growth to produce a vigorous, healthy plant, but the weather should be dry and not too warm while the plants are in bloom.
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

THE CONSEQUENCES OF AN OPEN FIELD BURNING BAN ON THE U.S. KENTUCKY BLUEGRASS SEED INDUSTRY [PDF]

open access: yes
An econometric model of the U.S. Kentucky bluegrass seed industry in the Pacific Northwest is specified and estimated in order to evaluate the short and long run consequences of yield reductions associated with a ban on open field burning of grass ...
Burt, Lawrence A.   +2 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Economic associations among causes of species endangerment in the United States. [PDF]

open access: yes
Associations among causes of species endangerment in the United States reflect the integration of economic sectors, supporting the theory and evidence that economic growth proceeds at the competitive exclusion of nonhuman species in the aggregate ...
Czech, Brian   +2 more
core   +1 more source

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