Results 61 to 70 of about 159,309 (302)
Fusion of Range and Stereo Data for High-Resolution Scene-Modeling [PDF]
This work has received funding from Agence Nationale de la Recherche under the MIXCAM project number ANR-13-BS02-0010-01.
Evangelidis, GD, Hansard, M, Horaud, R
core +4 more sources
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Some Insects Injurious to Red Clover [PDF]
Exact date of bulletin unknown.PDF pages ...
Parks, T. H.
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Computational intelligence approaches to robotics, automation, and control [Volume guest editors] [PDF]
No abstract ...
Chen, Yi +5 more
core
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
The peculiarities of sorghum seed-growing in the Rostov region
The peculiarities of sorghum seed-growing in the Rostov region To obtain high-qualitative seeds it’s necessary to improve seed-growing and to follow all recommendations concerning cultivation technology, harvesting, after-harvesting seed processing and ...
S. I. Gorpinichenko +4 more
doaj +1 more source
A novel neural network approach to cDNA microarray image segmentation [PDF]
This is the post-print version of the Article. The official published version can be accessed from the link below. Copyright @ 2013 Elsevier.Microarray technology has become a great source of information for biologists to understand the workings of DNA ...
Adams +52 more
core +1 more source

