Results 111 to 120 of about 1,441,030 (302)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Revista Brasileira de Fruticultura, 2012 Crataeva tapia L., espécie florestal pertencente à família Caparidaceae, conhecida popularmente como trapiá, é uma árvore frutífera de múltiplos usos na medicina popular, como madeireira e árvore ornamental. Dessa forma, objetivou-se definir substratos e
Edna Ursulino Alves +4 more
doaj
Removal of bunt spores from wheat seed lots by brush cleaning [PDF]
, 2005 Common bunt is infecting wheat seedling just after sowing, in the heterotrophic phase before seedling emergence. The seed per se is healthy at the time of sowing, but gets infected from spores resting on the seed surface. Bechel et al.
Borgen, Anders
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
An Analysis of the Supply for Seed Yams in Nigeria [PDF]
This study was conducted to examine the supply of seed yam in major yam producing areas of Northern and Southern Nigeria using the supply function analysis.
Akinpelu, A.O +7 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
HorticulturaePhaseolus lunatus L. is a species of landrace bean widely cultivated in Northeast Brazil. The integration of new technologies in the agricultural sector has highlighted the significance of seed images analysis as a valuable asset in the characterization ...
Emerson Serafim Barros +6 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Improvement of the quality of propagation material for organic farming system [PDF]
, 2006 The use of organic propagation material is obligatory according to the current EU regulations for organic production. However, frequently difficulties are en-countered regarding the availability, the costs or the quality.
Groot, S.P.C. +7 more
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