Results 51 to 60 of about 1,331,739 (313)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Using past planning practice to inform biodiversity net gain in residential developments

Ecological Solutions and Evidence
Urban growth is a major driver of biodiversity loss, as natural habitats are destroyed or fragmented. To address this, nature‐positive initiatives aim to balance development with nature conservation.
Ian Thornhill, Anna Gilchrist, Bethany Searle, Caglar Koksal, David Sampson   +4 more
doaj   +1 more source

Exploring the implementation of relational practice in a primary school to support school attendance

Frontiers in Education
School attendance difficulties are increasingly recognised as complex challenges, rooted in emotional, relational, and systemic influences. This study explores how relational practice can be implemented in a primary school to support attendance, using ...
George Alaimo, Catherine Kelly
doaj   +1 more source

Metabolic Disturbance Induced by the Embryo Contributes to the Formation of Chalky Endosperm of a Notched-Belly Rice Mutant

Frontiers in Plant Science, 2022
Grain chalkiness is a key quality trait of the rice grain, whereas its underlying mechanism is still not thoroughly understood because of the complex genetic and environmental interactions.
Yang Tao, Atta Mohi Ud Din, Lu An, Hao Chen, Ganghua Li, Yanfeng Ding, Zhenghui Liu, Zhenghui Liu   +7 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

The acid lipase of the castor bean. Properties and substrate specificity*

Journal of Lipid Research, 1962
A castor bean lipase with a pH optimum of 4.3 is found within the fatty layer obtained by centrifuging a homogenate of the bean; most of the fat may be removed by extraction with ethyl ether in the presence of saturated sodium chloride solution, yielding
Robert L. Ory, Allen J. St. Angelo, Aaron M. Altschul   +2 more
doaj   +1 more source

ZmnMAT1, a nuclear-encoded type I maturase, is required for the splicing of mitochondrial Nad1 intron 1 and Nad4 intron 2

Frontiers in Plant Science, 2022
Maturases can specifically bind to intron-containing pre-RNAs, folding them into catalytic structures that facilitate intron splicing in vivo. Plants possess four nuclear-encoded maturase-related factors (nMAT1-nMAT4) and some maturases have been shown ...
Kaijian Fan, Qinghui Fu, Qianhan Wei, Sinian Jia, Anqi Zhao, Tengteng Wang, Jie Cao, Yan Liu, Zhenjing Ren, Yunjun Liu   +9 more
doaj   +1 more source

Improving the Availability of Organic Forage Seed in Wales [PDF]

, 2004
The EU regulation requiring organic farmers to use 100% organic herbage seed is looming closer. Currently they are ‘enjoying’ a derogation from this because suitable seed is not available. For 2004 seeds mixtures had to contain at least 50% organic seed.
Marshall, Athole, McCalman, Heather
core  

Arabidopsis thaliana DOF6 negatively affects germination in non-after ripened seeds and interacts with TCP14

, 2011
Seed dormancy prevents seeds from germinating under environmental conditions unfavourable for plant growth and development and constitutes an evolutionary advantage.
Rueda Romero, Paloma, Barrero Sicilia, Cristina, Gomez Cadenas, Aurelio, Carbonero Zalduegui, Pilar, Oñate Sanchez, Luis   +4 more
core   +1 more source