Results 51 to 60 of about 129,721 (299)

Modelling the spatio-temporal pattern of primary dispersal in stone pine (Pinus pinea L.) stands in the Northern Plateau (Spain) [PDF]

open access: yes, 2012
Natural regeneration in stone pine (Pinus pinea L.) managed forests in the Spanish Northern Plateau is not achieved successfully under current silviculture practices, constituting a main concern for forest managers. We modelled spatio-temporal features
Awada   +56 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Distribution patterns and corresponding dispersal outcomes of seeds following secondary wind dispersal

open access: yesEcological Indicators
Seed dispersal outcomes such as antitelechory, atelechory, telechory, and seed storage, reflect plants' functional responses in dispersal. How diaspore attributes affect seed distribution patterns and corresponding dispersal outcomes following secondary ...
Wei Liang   +8 more
doaj   +1 more source

Quantifying patch‐specific seed dispersal and local population dynamics to estimate population spread of an endangered plant species

open access: yesEcology and Evolution, 2021
Aim Habitat loss and fragmentation impose high extinction risk upon endangered plant species globally. For many endangered plant species, as the remnant habitats become smaller and more fragmented, it is vital to estimate the population spread rate of ...
Jinlei Zhu   +3 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Pre-dispersal seed loss in two Prosopis species (Fabacea: Mimosoidea) from the Monte Desert, Argentina

open access: yesEcología Austral, 2018
Pre-dispersal flters imposed on the seed stage can alter the likelihood of seed dispersal. We evaluate pre-dispersal seed loss due to predation by insects and abortion in Prosopis flexuosa and P. chilensis. This study was conducted in two protected areas
Silvina Velez   +2 more
doaj   +1 more source

Spatial-scale dependencies in the predation of seeds by rodents [PDF]

open access: yes, 1995
Summary 1. Previous studies have shown rates of seed predation in deciduous woodland to be high (on average 60%) and extremely variable in space and time. 2.
Borelli, Teresa
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Regeneration in gap models: priority issues for studying forest responses to climate change [PDF]

open access: yes, 2001
Recruitment algorithms in forest gap models are examined with particular regard to their suitability for simulating forest ecosystem responses to a changing climate. The traditional formulation of recruitment is found limiting in three areas.
Clark, D.F.   +11 more
core   +2 more sources

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