Results 81 to 90 of about 73,989 (347)

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Sleeping Beauties, dormancy and resistance in harsh environments: molecular, proteomic and metabolomic aspects - Berlin, Germany, 18-20 May 2008 [PDF]

, 2008
Land degradation is a major problem in the semi-arid environments of Sub-Saharan Africa. Fighting land degradation is essential to ensure the sustainable and long-term productivity of the habited semiarid lands.
Hilhorst, H.W.M.
core   +7 more sources

Ecophysiology of seed dormancy and the control of germination in early spring-flowering Galanthus nivalis and Narcissus pseudonarcissus (Amaryllidaceae) [PDF]

, 2015
Seed dormancy induction and alleviation in the winter-flowering moist temperate woodland species Galanthus nivalis and Narcissus pseudonarcissus are complex and poorly understood.
Baskin, Baskin, Baskin, Baskin, Bishop, Blanchard, Bliss, Budnikov, Caldwell, Carpenter, Church, Copete, Davis, Fenner, Fiona R. Hay, Handel, Harper, Heinrich, Herranz, Herranz, Karssen, Kebreab, Kondo, Li, Marquis, Meerow, Mondoni, Mondoni, Mondoni, Murdoch, Newton, Nuñez, Pons, Probert, Richard H. Ellis, Rosemary J. Newton, Thanos, Thompson, Thompson, Vandelook, Vleeshouwers, Way   +41 more
core   +1 more source

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

STUDIES IN SEED DORMANCY [PDF]

New Phytologist, 1967
SummaryThe dormancy of hazel seeds (Kent cob nuts) has been found to be broken by less than 30 days chilling at 5° C. During 50 days chilling there was no detectable growth of the embryonic axes although growth rapidly commenced when the temperature of 50‐day chilled seeds was raised to 20° C.Both cotyledon slices and embryonic axes from dormant seeds ...
J. W. BRADBEER, B. COLMAN
openaire   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Evaluation of the risks of contaminating low erucic acid rapeseed with high erucic rapeseed and identification of mitigation strategies [PDF]

, 2019
High erucic acid rapeseed (HEAR) oil is under increasing demand for various industrial applications. However, many growers are concerned that if they grow the crop, they will not be able to revert to other rapeseed varieties in the future due to the risk
Bennett, Bilsborrow, Brookes, Carter, Downey, Eastern, Friedt, Henry, Ingram, Kightley, Knutsen, Kramer, Lutman, Messéan, Moyes, Norris, Robson, Sovero, Squire, Squire, Sweet, Söchting, Zanettti   +22 more
core   +2 more sources

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

Advanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava, Alireza Rafieerad, Weiang Yan, Keshav Narayan Alagarsamy, Qingdong Guan, Leena Regi Saleth, Michel Aliani, Sanjiv Dhingra   +7 more
wiley   +1 more source

Carbon Nanotubes Improved the Germination and Vigor of Plant Species from Peatland Ecosystem Via Remodeling the Membrane Lipidome

Nanomaterials, 2020
Application of the nanopriming technique to alleviate seed dormancy has shown promising results in various agricultural crop species. However, there is a dearth of knowledge regarding its potential use in native peatland boreal forest species to ...
Md. Hossen Ali, Jean-Marie Sobze, Thu Huong Pham, Muhammad Nadeem, Chen Liu, Lakshman Galagedara, Mumtaz Cheema, Raymond Thomas   +7 more
doaj   +1 more source