Results 181 to 190 of about 882,341 (296)

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

Advanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo, Qianqian Zhang, Chenhao Wang, Zhiheng Yi, Alex Jinpeng Wang, Jing Tang, Min Li   +6 more
wiley   +1 more source

Development of Grape Seed Extract-Fortified Biscuits: Effects on Dough Rheology, Biscuit Quality, Antioxidant Activity, and Sensory Evaluation. [PDF]

Foods
Jiao R, Zhang F, Yang L, Wang C.
europepmc   +1 more source

Thermodynamics and Kinetics in Host Design for Dendrite‐Free Zinc Metal Anodes

Advanced Science, EarlyView.
This review comprehensively summarizes recent advances in host design strategies for high‐performance zinc metal anodes, and deeply elucidates their thermodynamic and kinetic design principles from the perspective of surface modification, interface engineering, and spatial confinement.
Peng Xiao Sun, Quanwei Ma, Yangyang Liu, Longhai Zhang, Rui Wang, Yu‐Hui Zhu, Tengfei Zhou, Sen Xin, Le Yu, Chaofeng Zhang   +9 more
wiley   +1 more source

Physicochemical and structural properties of dough and cookies formulated with <i>Hodgsonia heteroclita</i> oilseed cake as a functional fat replacer. [PDF]

Food Chem X
Jibril Isah Y, Suttisansanee U, Khemthong C, Chaveanghong S, Chupeerach C, Chamchan R, On-Nom N.   +6 more
europepmc   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

Advanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang, Shuiping Fu, Ye Xu, Jia Gao, Jiwei Ren, Xu Yang, Hesong Xu, Ge Sun, Yanjie Li, Yanlin Wang, Lu Jin, Peijuan Chen, Ying Xu, Jianhao Li, Hua Lin, Chujiao Hu, Kaixian Chen, Huan Xiong, Cheng Luo, Shijie Chen   +19 more
wiley   +1 more source

Barteldes Seed : [catalog]

1923 Barteldes ...
Barteldes Seed Company.
core  

Valorization of <i>Nigella sativa</i> Seed Meal and Whey as Functional Ingredients to Enhance Nutritional, Rheological and Sensory Properties of Rice-Based Gluten-Free Bread. [PDF]

Foods
Sanah I, Djeghim F, Arici M, Ozgolet M, Ozturk E, Babouche K, Cherak S, D'Elia M, Rastrelli L.   +8 more
europepmc   +1 more source

Restoration of m6A‐Modified circPSMB1 Suppresses Chordoma Progression and Enables Local Nanotherapeutic Intervention

Advanced Science, EarlyView.
An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang, Liang Qiu, Xingbang Ruan, Yihan Shi, Ye Wang, Hanwen Li, Kai Zhang, Kangwu Chen   +7 more
wiley   +1 more source

Optimization of Mechanical Structure for Pomegranate Peeling and Low-Damage Seed Extraction Technology Based on Mechanical Property Analysis: A Comprehensive Review. [PDF]

Int J Food Sci
Zhu E, Ran J, Li L, Zhu J.
europepmc   +1 more source

Water‐Soluble POSS Promotes Concurrent Coalescence and Crosslinking for Multiscale‐Reinforced, Coalescent‐Free Waterborne Coatings

Advanced Science, EarlyView.
Water‐soluble amine‐functionalized polyhedral oligomeric silsesquioxane promotes concurrent latex coalescence and crosslinking, allowing epoxy‐functional particles to form continuous films without added volatile coalescing agents. The resulting multiscale‐reinforced waterborne coatings combine high strength, toughness, optical transparency, scratch ...
Chao Wang, Bin Wu, Lin Li, Yibo Ru, Xiaohe Zhang, Minlong Wang, Ruoyan Yang, Jie An   +7 more
wiley   +1 more source