Results 91 to 100 of about 3,566,202 (337)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Ecology and Evolution, 2021 Comparative studies of invasive, noninvasive alien, and native congenic plant species can identify plant traits that drive invasiveness. In particular, functional traits associated with rapid growth rate and high fecundity likely facilitate invasive ...
Sunghyun Woo +4 more
doaj +1 more source
Natural regeneration of broadleaved tree species in southern Sweden [PDF]
, 2001 The objective of the present thesis was to examine the effects of silvicultural treatments and seed dispersal from surrounding stands on the establishment of natural regeneration of broadleaved tree species in southern Sweden.
Karlsson, Matts
core
Morphological Characteristics of Weed Seed Fibers
Weed & Turfgrass Science, 2014 In this study, to obtain basic data for searching potential resources as new natural fibers, we investigated morphological and classificatory characteristics of 21 weed seed fibers. According to classification keys in this study, the collected weed seed fibers could be classified into total 13 types, showing their diversity.
A Ra Yoon +3 more
openaire +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Physical Seed Characteristics of Clary Sage (Salvia sclarea L.) at Different Altitudes in Denizli
ISPEC Journal of Agricultural SciencesThis study investigates the geographic variation in the physical seed characteristics of clary sage (Salvia sclarea L.) collected from diverse locations within Denizli province, Türkiye.
Tansu USKUTOĞLU
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Revista Brasileira de Fruticultura, 2013 A poliembrionia é um caráter fundamental no melhoramento genético e na multiplicação comercial de porta-enxertos de citros. Este trabalho avaliou as relações entre poliembrionia e diferentes atributos morfológicos de sementes de 12 genótipos de citros ...
Fernanda Emilia Vital de Oliveira Duarte +4 more
doaj
Acta Societatis Botanicorum Poloniae, 2014 In this work the results of studies on the seed morphology of 6 native species of the genus Ribes L.: R. uva-crispa L., R. nigrum L., R. alpinum L., R. petraeum Wulfen, R. rubrum L. and R. spicatum Robson are presented.
Dorota Wrońska-Pilarek
doaj +1 more source
Frontiers in Plant Science, 2020 Cannabis sativa L. (hemp, marijuana) produces male and female inflorescences on different plants (dioecious) and therefore the plants are obligatory out-crossers.
Z. Punja, J. Holmes
semanticscholar +1 more source