Results 151 to 160 of about 191,044 (310)

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Broadband, Flexible, Skin‐Compatible Carbon Dots/Graphene Photodetectors for Wearable Applications

Advanced Functional Materials, EarlyView.
Broadband, flexible photodetectors integrating nitrogen‐rich carbon dots with single‐layer graphene on plastic substrates are demonstrated. A biocompatible chitosan–glycerol electrolyte enables efficient low‐voltage gating and on‐skin operation. The devices exhibit ultraviolet‐to‐near‐infrared response, mechanical robustness under bending, and verified
Nouha Loudhaief, Petr Rozhin, Ilaria Bertuol, Ali Raza, Leonardo Viti, Subhankar Roy, Enrico Cavarzerani, Luca Sbuelz, Matteo Brilli, Andrea Serinolli, Jacopo Nicoletti, Riccardo Piccoli, Sebastián Castilla, Simone Dal Zilio, Enrique Rodríguez‐Castellón, Miriam Serena Vitiello, Maurizio Selva, Flavio Rizzolio, Alvise Perosa, Giovanni Antonio Salvatore, Domenico De Fazio   +20 more
wiley   +1 more source

The ppGpp-HpaR1-gum regulatory pathway modulates exopolysaccharides production in Xanthomonas campestris pv. campestris

npj Biofilms and Microbiomes
Exopolysaccharides (EPS) are critical components of the biofilm matrix, and ppGpp has been demonstrated to positively influence biofilm formation. Here, we elucidate the underlying mechanism by which ppGpp regulates EPS production by facilitating HpaR1 ...
Kaihong Bai, Xiaoli Xu, Chengxuan Yu, Huayu Yan, Miaomiao Lyu, Na Jiang, Jianqiang Li, Jingnan Zhang, Zhenlong Wang, Laixin Luo   +9 more
doaj   +1 more source

Ionic‐Electronic Hydrogel‐Liquid Metal Composite Bilayer with Tissue‐Adaptive and Adhesive Properties for Closed‐Loop Neuroprosthetic System

Advanced Functional Materials, EarlyView.
A hydrogel–liquid metal composite peripheral nerve interface (HLB‐PNI) combines electrically durable electrodes and tissue‐adhesive hydrogel for tissue‐adaptive implantation. In nerve‐injured rats, it enables the diagnosis of sensory‐motor connectivity via stimulation and neural signal recording.
Yewon Kim, Kyoungryong Kim, Jaehyon Kim, Heewon Choi, Mikyung Shin, Donghee Son   +5 more
wiley   +1 more source

Controlling 3D Contractility via Engineered Fibrous Hydrogel Composites

Advanced Functional Materials, EarlyView.
A tunable composite contractile assembly (CCA) is developed that can permit or resist contraction without changing cell‐adhesion and density, unlike collagen whose inherent coupling of these ECM cues limits its use as a platform in contractility studies.
Karen L. Xu, Yuqi Zhang, Alysse DeFoe, Georgios Kotsaris, Brendan Stoeckl, Matthew D. Davidson, Jason A. Burdick, Robert L. Mauck   +7 more
wiley   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source

Effects of Stenocarpella maydis in seeds and in the initial development of corn

Journal of Seed Science
The association of the fungus Stenocarpella maydis with corn seed may cause a reduction of seed germination and vigor of the emerged seedlings. This work was carried out in order to evaluate the effects of S. maydis on corn seed quality as well as on its
Carolina da Silva Siqueira, Ellen Noly Barrocas, José da Cruz Machado, Ursula Abreu da Silva, Iara Eleutéria Dias   +4 more
doaj  

Dense Nanofibrillar Collagen–Silica Hybrids with High Strength and ECM‐Mimetic Tissue Integration

Advanced Functional Materials, EarlyView.
Dense nanofibrillar collagen–silica hybrids are engineered by synchronizing collagen fibrillogenesis with silica condensation, producing printable scaffolds that unexpectedly approach native extracellular matrix organization and strength. These cell‐free constructs guide endogenous cell‐infiltration, enable localized matrix remodeling, and integrate ...
Norein Norein, Shima Tavakoli, Philipp Wolf, Xie Ling, Veronica Rondahl, Klaus Leifer, Gry Hulsart‐Billström, Jöns Hilborn   +7 more
wiley   +1 more source

Detection and quantification of Xanthomonas axonopodis pv. phaseoli and its variant fuscans in common bean seeds

Journal of Seed Science
The common bacterial blight of common beans (CBCF), a disease caused by Xanthomonas axonopodis pv. phaseoli (Xap) and Xanthomonas axonopodis pv. phaseoli var. fuscans (Xapf), significantly reduces grain yield and seed quality.
Norimar D'Ávila Denardin, Vanessa Andréia Agostini   +1 more
doaj