Results 91 to 100 of about 282,702 (307)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Long-term storage-dependent changes in seed physiological aspects of Hyoscyamus niger from a cold desert region of Trans-Himalaya

open access: yesInternational Journal of Plant Biology, 2010
Henbane (Hyoscyamus niger L.), an economically important medicinal plant, has an endangered status in Himachal Pradesh (India) that needs appropriate conservation interventions. We have examined seed physiological aspects of H.
Shashi Sharma, Rajender Kumar Sharma
doaj   +1 more source

Preliminary Functional-Structural Modeling on Poplar (Salicaceae) [PDF]

open access: yes, 2009
Poplar is one of the best fast-growing trees in the world, widely used for windbreak and wood product. Although architecture of poplar has direct impact on its applications, it has not been descried in previous poplar models, probably because of the ...
Cao, Weiqun   +6 more
core   +4 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Alterations in carbon and nitrogen metabolism under phenylalanine ammonia-lyase inhibition in winter triticale seedlings

open access: yesScientific Reports
This study aimed to assess the impact of phenylalanine ammonia-lyase (PAL) inhibition on the carbon and nitrogen metabolism of winter triticale seedlings using 4-hydroxybenzoic acid hydrazide (HBH, 10⁻³ M), with particular attention to sugar accumulation
Katarzyna Hura   +3 more
doaj   +1 more source

Testes de deterioração controlada e envelhecimento acelerado para avaliação do vigor em nabo forrageiro

open access: yesRevista Ciência Agronômica
O objetivo do trabalho foi verificar a eficiência de diferentes procedimentos para condução dos testes de envelhecimento acelerado e deterioração controlada visando avaliação da qualidade fisiológica de sementes de nabo forrageiro (Raphanus Sativus L ...
Camila Santos Barros de Morais   +1 more
doaj   +1 more source

Physiological Study of Maple Seeds [PDF]

open access: yesBotanical Gazette, 1920
River maple 1. Seeds lose their viability when the water content is reduced to 30-34 per cent. 2. Temperature seems to play no part in determining the critical point of water loss. Higher temperatures only hasten the rate at which the point of desiccation is attained. 3. Respiratory activity in the desiccating seeds at 25⚬C.
openaire   +1 more source

Programmed cell death and genetic stability in conifer embryogenesis [PDF]

open access: yes, 2007
Somatic embryogenesis, the generation of embryos from somatic cells, is a valuable tool for studying embryology. In addition, somatic embryos can be used for large-scale vegetative propagation, an application of great interest for forestry.
Helmersson, Andreas
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Using the optimal seed germination temperature approach to determine the potential distribution of Inga jinicuil in Mexico under climate change scenarios

open access: yesScientific Reports
Inga jinicuil is used extensively in shade coffee farms in Mexico, a diversified agroforestry system providing important environmental goods and services. However, its recalcitrant seeds represent an important barrier to its propagation.
Salvador Sampayo-Maldonado   +11 more
doaj   +1 more source

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