Results 101 to 110 of about 282,702 (308)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Physiological Study of Maple Seeds [PDF]

open access: yesBotanical Gazette, 1920
River maple 1. Seeds lose their viability when the water content is reduced to 30-34 per cent. 2. Temperature seems to play no part in determining the critical point of water loss. Higher temperatures only hasten the rate at which the point of desiccation is attained. 3. Respiratory activity in the desiccating seeds at 25⚬C.
openaire   +1 more source

Programmed cell death and genetic stability in conifer embryogenesis [PDF]

open access: yes, 2007
Somatic embryogenesis, the generation of embryos from somatic cells, is a valuable tool for studying embryology. In addition, somatic embryos can be used for large-scale vegetative propagation, an application of great interest for forestry.
Helmersson, Andreas
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

POMONA: a multiplatform software for modeling seed physiology. [PDF]

open access: yesFront Plant Sci, 2023
Cantão RF   +5 more
europepmc   +1 more source

Physiological maturity of pumpkin seeds

open access: yesAfrican Journal of Agricultural Research, 2015
The objective of this study was to evaluate the physiological changes of pumpkin seeds during the maturation process. Thereby, the study was conducted in the municipality of Juazeiro, at the experimental area of the State University of Bahia. Seeds of the cultivar ‘Maranhao’ were harvested from fruits at regular intervals, every 10 days, from 15 to 60 ...
F Neto Acacio   +3 more
openaire   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Ethylene-independent promotion of photomorphogenesis in the dark by cytokinin requires COP1 and the CDD complex [PDF]

open access: yes, 2019
The transition of skotomorphogenesis to photomorphogenesis is induced by the perception of light, and is characterized by the inhibition of hypocotyl elongation and opening of cotyledons.
Cortleven, Anne   +3 more
core   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

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