A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Maintaining Onion Seed Quality during Storage Through Seed Priming
Background: Seed is an important component and the quality seed plays a crucial role in agricultural production as well as in the national economy. Availability of viable and vigorous seeds at the planting time is important. Onion seeds have a short life span among the vegetable crops and lose viability rapidly after harvest.
V.P.S. Panghal +3 more
openaire +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
The Effect of Salicylic Acid and Gibberellin on Seed Reserve Utilization, Germination and Enzyme Activity of Sorghum (Sorghum bicolor L.) Seeds Under Drought Stress [PDF]
Seed priming methods have been used to increases germination characteristics under stress conditions. The study aimed was to determine the effect of salicylic acid and gibberellin on seed reserve utilization, germination and enzyme activity of sorghum ...
Mohammad Sedghi +3 more
core
Priming Benih Padi (Oryza Sativa L.) dengan Zn untuk Meningkatkan Vigor Bibit pada Cekaman Terendam [PDF]
Seed priming has been widely used to improve seedling vigor of several crops such as corn, wheat, and rice. Seed priming with zinc to increase seedling tolerance on submergence stress had never been evaluated.
Hasmeda, M. (Mery) +3 more
core +3 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Low germination and vigor of rice seed associated with dry-seed broadcasting are common problems encountered by rice growers. The objectives of this study were to evaluate the role of potassium nitrate (KNO3) on the pattern of seed imbibition and to ...
Anisa Ruttanaruangboworn +3 more
doaj +1 more source
Priming with potassium solutions improves seedling growth and vigor in forage sorghum (Sorghum bicolor L.) [PDF]
In this study a laboratory experiment was conducted to assess the effect of different potassium priming sources on seedling growth and vigor of sorghum genotypes. Priming with KH2PO4 gave best results for SOG (23.052), RL (19.667) and VI (2,291.9).
Chauhan, Priyamvada +2 more
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Standardization of Seed Hydro-priming Duration in Bitter Gourd, Momordica Charantia L.
Presowing seed priming helps to improve germination and stand establishment. However, before priming the seeds, it is important to establish the safe limits of priming durations.
D. K. Mehta +4 more
doaj

