Results 111 to 120 of about 56,614 (300)

Effect of NaCl priming duration and concentration on germination behavior of Tunisian safflower [PDF]

open access: yes, 2012
Priming is an effective technique that improves germination of several crop species. That’s why this study was carried in order to evaluate the effect of NaCl seed priming techniques on germination and early growth of safflower (Carthamus tinctorius L.).
Elouaer Mohamed Aymen, Hannachi Cherif
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Effect of Drought Stress and Seed Priming on some Vegetative and Reproductive Traits of Castor bean (Ricinus Communis L.) var Esfahan [PDF]

open access: yesIkufīziyuluzhī-i Giyāhān-i Zirā̒ī, 2018
Drought is an important factor affecting germination, early plant growth and its rate and decreasing economic performance of seedlings. Thus, seed priming to induce homogenice germination, emergence and increase the rate of growth and reduce adverse ...
Sonia Abasi Sadr   +2 more
doaj  

Seed enhancements [PDF]

open access: yes, 2017
Seed enhancements may be defined as post-harvest treatments that improve germination or seedling growth, or facilitate the delivery of seeds and other materials required at the time of sowing. This definition includes three general areas of enhancements:
Allen, P. S.   +5 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Promotive Effect of Priming with 5-Aminolevulinic Acid on Seed Germination Capacity, Seedling Growth and Antioxidant EnzymeActivity in Rice Subjected to Accelerated Ageing Treatment

open access: yesPlant Production Science, 2015
Seed deterioration by ageing caused by natural and artificial treatments lowers germinability and viability. Seed priming is a technique used to relieve seed deterioration from ageing.
Uthaiwan Kanto   +4 more
doaj   +1 more source

Perlakuan Invigorasi untuk Meningkatkan Mutu Fisiologis dan Kesehatan Benih Padi Hibrida Intani-2 Selama Penyimpanan [PDF]

open access: yes, 2014
Storage condition and pathogen infection of seed can cause seed deteriorates faster. The rate of deterioration during storage could be slowed by seed invigoration, and pathogen infection could be elimited by application of natural pesticide.
Ilyas, S. (Satriyas)   +2 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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