Results 91 to 100 of about 1,093,092 (310)
Food Chemistry: XThis study explored the effects of enzymatic debranching (ED, 0–12 h) and high hydrostatic pressure (HHP, 300–600 MPa) on the multi-scale structure and in vitro digestibility of lotus seed starch (LS)–conjugated linoleic acid (CLA) microcapsules.
Bailong Wang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Delivering Seeds of 'Orphan' Crops: The Case Studies of Potato and Groundnut in India [PDF]
This paper examines the performance of the Indian seed system in the context of high volume, low value seed, using the case studies of potato and groundnut.
Mathur, Prasoon +2 more
core +1 more source
Die BodenkulturChickpea, a high-quality protein source, is still rarely cultivated in Austrian agriculture, although its high drought tolerance would make it a suitable alternative crop in the eastern arid growing regions, where climate change increasingly causes ...
Bomers Svenja +6 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Biological activity of glucosinolate derived compounds isolated from seed meal of Brassica crops and evaluated as plant and food protection agents [PDF]
, 2007 Glucosinolates are amino acid derived allelochemicals characteristic of plants of the order Capparales. These compounds are present in seeds of agriculturally common Brassica crops in varying quantities depending on the species (ref).
Bellostas, N. +8 more
core
The local crop varieties (farmers’ varieties) registration system in Nepal: Past, present and future
Genetic ResourcesFarmers’ varieties, characterized by their broad genetic base and ecological resilience, were historically not recognized by Nepal’s formal seed system.
Bal Krishna Joshi +3 more
doaj +1 more source
Effect of Pansy (Viola x wittrockiana gams) Seeds Colour and Size on their Germination
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2008 Four commercial seed lots from the Polish seed companies of pansy (Viola x wittrockiana Gams) with low germination capacity were sorted into 2 size fractions: small and large: below 4 mm long and above 4 mm and 3 colour fractions: yellow, brown and dark,
Rosinska AGNIESZKA, Roman HOLUBOWICZ
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source