Results 101 to 110 of about 7,480,106 (305)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Characterisation of brush-harvested hayseed quality (purity, seed content and germination) for the calculation of optimal sowing densities [PDF]

open access: yes, 2017
Several projects demonstrate the utility of hayseed for ecological restoration, but how hayseed should be employed remains ambiguous as no standard procedure currently exists for hayseed characterisation.
R. M. CERIANI   +5 more
core   +2 more sources

EFFECT OF TRANSPLANTING DATE ON YIELD AND SEED QUALITY OF T. AMAN RICE VARIETIES [PDF]

open access: yes, 2021
A Thesis submitted to the Institute of Seed Technology, Sher-e-Bangla Agricultural University, Dhaka in partial fulfilment of the requirements for the degree of MASTER OF SCIENCE (MS) IN SEED TECHNOLOGYA field experiment was conducted in
HASAN, MD. MEHEDE
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Seed development, yield and quality of two palm species growing in different tropical forest types in SE Brazil: implications for ecological restoration

open access: yes, 2011
Natural forest remnants have been set as seed production fields to supply seeds of native tree species for tropical forest restoration, but the effect of different forest types on seed production has not been accessed to date for palm species.
RODRIGUES, R. R.   +2 more
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Barley seed survey shows quality problems

open access: yesCalifornia Agriculture, 1963
Only 20% of the barley seed lots sampled in a two-year, 17-county survey—as reported in this study—met standards required of California certified barley seed.
M Miller, C Schaller, E Bruch, F Parsons
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Seed Business Management in Africa [PDF]

open access: yes
Seed industry, Seed production, Trade, Commodity markets, Marketing, Agribusiness, Crop Production/Industries, E10, E20, E21, E70, E73, F03,
MacRobert, John F.
core  

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