Results 91 to 100 of about 7,480,106 (305)

VARIETAL SALES AND QUALITY DIFFERENTIATION: THE CASE OF CERTIFIED SOYBEAN SEED IN THE SOUTHEASTERN U.S. [PDF]

open access: yes
Variation in annual soybean plantings contributes to uncertainty in supplies of and demand for soybean seed in the southeastern U.S. This study used an expenditure valuation approach in an hedonic analysis framework to estimate returns to soybean seed ...
Houston, Jack E.   +2 more
core  

Lifting quality constraints to agricultural technology adoption in the Ugandan market for maize seed

open access: yes, 2023
Agricultural technology remains under-adopted among smallholder farmers in sub-Saharan Africa. We investigate how the (perceived) quality of an agricultural input affects its adoption by means of two interventions.
http://orcid.org/0000-0003-2404-7826 Van Campenhout, Bjorn; http://orcid.org/0000-0002-6889-7358 Spielman, David J.   +1 more
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

The local crop varieties (farmers’ varieties) registration system in Nepal: Past, present and future

open access: yesGenetic Resources
Farmers’ varieties, characterized by their broad genetic base and ecological resilience, were historically not recognized by Nepal’s formal seed system.
Bal Krishna Joshi   +3 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Farmers, seeds and varieties : supporting informal seed supply in Ethiopia [PDF]

open access: yes, 2008
Ethiopia is characterized by an enormous diversity in agro-ecosystems, crops and varieties, with the informal seed systems dominant in seed supply for almost all crops.
Thijssen, M.H.   +3 more
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Impact of early seed quality selection on maize inbreds and hybrids [PDF]

open access: yes, 2007
Seed composition, genetic background, and environment influence seed quality. Plant breeders selecting for improved seed composition seldom select their inbreds for improved seed quality traits. The standard germination test evaluates seed viability, but
Pollak, L.   +6 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Yield and quality of carrot seeds, cv. Brasília, as a result of plant population, gibberellic acid and stage of maturity

open access: yes, 2004
'Brasília' is a cultivar of carrot with characteristics suiting cultivation under hot conditions but with problems in seed production, arising from the conflicting requirements of root and seed production.
Barbedo, A. S.C.   +4 more
core   +1 more source

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