Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
VARIETAL SALES AND QUALITY DIFFERENTIATION: THE CASE OF CERTIFIED SOYBEAN SEED IN THE SOUTHEASTERN U.S. [PDF]
Variation in annual soybean plantings contributes to uncertainty in supplies of and demand for soybean seed in the southeastern U.S. This study used an expenditure valuation approach in an hedonic analysis framework to estimate returns to soybean seed ...
Fletcher, Stanley M. +2 more
core +1 more source
Control of seed borne diseasees in organic seed propagation [PDF]
, 2004 Introduction The key control measure of plant diseases in organic agriculture is crop rotation, mixed cropping and moderate fertilization. A wide range of plant diseases can be controlled or minimized in this way.
Borgen, Anders
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
The effect of nitrogen, fungicide, time and method of harvest on seed quality in super sweetcorn (Zea mays L.) cv. Illini gold : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Plant Science (Seed Technology) at Massey University [PDF]
, 1996 Super sweetcorn (Zea mays L.) poses problems for seed production, because the high seed sugar levels delay seed drying, which means harvest delays and the encouragement of pathogen invasion. These factors reduce seed quality, particularly germination and
Chompukeaw, Winai
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Relationship between seed harvesting method and seed physiological quality for a number of Pioneer maize hybrids [PDF]
, 2012 The seed germination and seed vigor of eight Pioneer Hi-Bred maize hybrids were evaluated immediately after harvesting and a year later. The aim was to determine whether the seed showed loss of germination and vigor when shelled mechanically.
Anda, Angéla +3 more
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Is it possible to check micro ginning fiber quality preservation performance using reference seed-cotton materials? [PDF]
, 2016 In sub-Saharian countries, simple micro-gin, without seed-cotton cleaner nor lint-cleaner, is often used as a reference device for characterizing the performance of industrial gin plants for fiber quality preservation.
Gourlot, Jean-Paul +3 more
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Assessment of On‐Farm Saved Chickpea (Cicer arietinum L.) Seed Quality in Central Ethiopia
Legume ScienceLimited information exists on the impact of current seed storage methods on seed quality in Central Ethiopia. The study aimed to assess the extent of the decline in seed quality of on‐farm stored chickpeas. Two hundred two farmers were identified using a
Abebe Sori +4 more
doaj +1 more source