Results 171 to 180 of about 2,387,160 (293)

Genetic Mapping and Transcriptomic Analysis of Sepal-Derived Seed Shape in Spinach. [PDF]

Int J Mol Sci
Fatima M, Ma X, Khalid E, Ming R.
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

A trans-species cytoplasmic polymorphism is associated with seed shape and aridity across multiple species of sunflowers. [PDF]

Proc Natl Acad Sci U S A
Owens GL, Cai Z, Bercovich N, Todesco M, Lee-Yaw JA, Rieseberg LH.   +5 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Control of seed-borne pathogens on vegetables by microbial and other alternative seed treatments

, 2004
In the EU-project "Seed Treatments for Organic Vegetable Production" (STOVE) physical and biologfoal methods aimed at the control of seed-borne vegetable pathogens are being investigated.
Koch, Eckhard, Schmitt, Annegret, Amein, Tahsein, Wright, Sandra, Wolf, Jan van der, Roberts, Steve, Tinivella, Federico, Gullino, Maria Lodovica, Groot, Steven   +8 more
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

The Seed Industry for Dryland Crops in Eastern Kenya [PDF]

The development and promotion of improved crop varieties as well as efficient seed production, distribution, and marketing systems have contributed significantly to increased agricultural production and food security in Kenya. However, these impacts have
Njoroge, Kiarie, Muhammad, Lutta, Mwangi, Wilfred, De Groote, Hugo, Verkuijl, Hugo, Bett, Charles   +5 more
core  

A meta-analysis on the relationship between seed size, seed shape and persistence in soil seed bank

Pakistan Journal of Botany, 2021
Yaya Guo, Weihua Lu, Zhaobi Che, Jiamin Cao, Hanjun Yang, Xingyu Huang   +5 more
openaire   +1 more source