Results 41 to 50 of about 15,087 (249)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Improving sorghum seed vigor by priming

open access: yesIOP Conference Series: Earth and Environmental Science, 2022
Abstract Sorghum (Sorghum bicolor L. Moench) is the fifth most important cereal that is widely used for food, feed, and industrial purposes. Sorghum is cultivated mostly in the central and eastern parts of Indonesia. Sorghum seed viability and vigor influence its productivity by affecting crop growth and stand establishment. Invigoration
R Arief   +3 more
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Effect of various shapes of seed and initial germination percent on vigor and its relationship with seedling field emergence of hybrid maize (Zea mays L.,) single cross 704 [PDF]

open access: yesعلوم و فناوری بذر ایران, 2017
In order to study on effect of hybrid maize single cross 704 having different primary germination percent various seed shapes on vigor and seedling field emergence, research was conducted at Seed and Plant Certification and Registration Institute (SPCRI)
Sh. Hashemi Fesharaki   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Seed Vigor and Field Performance of Winter Oilseed Rape (Brassica napus L.) Cultivars

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2010
The effect of seed vigor on field performance of two oilseed rape cultivars (Licord and Okapi) was investigated in 2008 at the Research Farm of the University Tabriz, Iran.
Kazem GHASSEMI-GOLEZANI   +3 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Vigor of sunflower and soybean aging seed [PDF]

open access: yesHelia, 2012
Seed aging and deterioration affect seed vigor and viability. The characteristics of the chemical composition of oil crops seed are related to specific processes occurring in the seed during storage. This study was performed to examine the changes in seed vigor of different sunflower and soybean genotypes under controlled and ...
Tatić, Mladen   +5 more
openaire   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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