Results 61 to 70 of about 23,811 (279)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Crop Journal, 2016 Seed aging decreases the quality and vigor of crop seeds, thereby causing substantial agricultural and economic losses in crops. To identify genetic differences in seed aging between homozygotes and heterozygotes in maize, the seeds of a set of ...
Bin Wang +5 more
doaj +1 more source
Biochemical Aspects of Seed Vigor
HortScience, 1980 Abstract It is beyond the purpose of this presentation to review all the definitions for the term “vigor” as applied to seeds. So far, no one definition has been accepted, and perhaps it is not yet time to settle on one definition until we know more about the subject.
openaire +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Electrical conductivity for seed vigor test in sorghum (Sorghum bicolor) [PDF]
, 2016 The objectives of this study were to obtain electrical conductivity test method for seed vigor test in sorghum, to recognize relationship between electrical conductivity test and potassium leakage, and to recognize relationship between electrical ...
Khodratien, Fatonah +2 more
core +1 more source
FRUIT AND SEED MORFOMETRY, SEED GERMINATION AND SEEDLING VIGOR of Parkia gigantocarpa
FLORESTA, 2019 The objectives of this work were to characterize fruits and seeds and evaluate seed germination and seedling vigor from fifteen parent plants of Parkia gigantocarpa Ducke. The fresh weight, length, width, and thickness of fruits and seeds were determined.
Demétrio Barros, Hellen Síglia +3 more
openaire +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Recent approaches for bell pepper seed vigor testing. [PDF]
, 2014 Seed vigor is a major attribute in the determination of whether a seed lot can be commercialized. Different physiological tests are used to assess seed vigor and are generally based on different concepts, which could lead to variable interpretations ...
MONDO, V. H. V. +2 more
core +1 more source