Results 51 to 60 of about 39,401 (308)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Effects of some chemical treatments on standard germination, field emergence and vigour in hybrid maize seeds [PDF]
, 2018 The main aim of this experiment was to investigate the possible effects of some active ingredients and their combinations, commonly adopted for maize seed treatment in Italian agriculture, on seed germination, vigour (cold test) and field emergence ...
Baldini, Mario +2 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
The Indian Journal of Agricultural SciencesThe study was carried out during summer seasons of 2021 and 2022 at ICAR-National Bureau of Plant Genetic Resources, New Delhi to evaluate 200 ridge gourd [Luffa acutangula (L.) Roxb.] germplasm accessions from India’s national genebank for 14 ...
MONIKA JHA +4 more
doaj +1 more source
Effect of soybean seed priming on germination and vigour depending on the seed lot and sowing date [PDF]
Ratarstvo i Povrtarstvo, 2014 The objective of this paper was to examine the effect of seed lot, sowing date, and priming on germination and vigour of soybean seed. Three different seed lots of an old soybean variety (Lot 1, Lot 2, Lot 3) created at the Institute of Field and ...
Miladinov Zlatica +5 more
doaj +1 more source
The Indian Journal of Agricultural Sciences, 2023 The experiment was conducted in the Department of Seed Science and Technology, B A College of Agriculture, Anand Agricultural University, Anand to know the influence on seed quality parameters under different temperature and artificial ageing treatment ...
VRUSHANK TRIVEDI +3 more
doaj +1 more source
Seed Vigour Evaluation of Rocket (Eruca sativa Mill.) Seed Lots
Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2020 The work was carried out to test the seed vigour test to correlate seedling emergence potential of rocket seed lots in the field conditions. Standard laboratory germination percentages of the 12 seed lots were ranged between 87 and 93%. Radicle emergence (2 mm) percentages after 18 (RE18h), 24 (RE24h), 36 (RE36h) and 48 (RE48h) during standard ...
Eren ÖZDEN +4 more
openaire +3 more sources
The need for a supply of high quality organic vegetable seeds [PDF]
, 2006 Production of high quality organic vegetable seeds encounters several challenges. Research is performed to support seed companies in producing vigorous and healthy organic vegetable seeds.
Groot, S.P.C. +7 more
core +2 more sources
Response of different wheat varieties towards Azospirillum and phosphate solubilizing bacteria (PSB) seed inoculation [PDF]
, 2016 Present investigation was undertaken to utilize Azospirillum and Phosphate Solubilizing Bacteria (PSB) to avail atmospheric nitrogen and soluble phosphate in soil for the wheat crop.
Chakrabarti, S. K. +3 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source