Results 61 to 70 of about 977 (213)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Dependence of the legume seeds vigour on their maturity and method of harvest

Acta Societatis Botanicorum Poloniae, 2014
Several methods were used to study 'the vigour and viability of legume seeds (Pisum sativum L. cv. Hamil, Piston arvense L. cv. Mazurska and Lupinus luteus L. cv. Tomik) harvested at three main stages of seed repening (green, wax and full).
Stanisław Grzesiuk, Ryszard Górecki
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Effect of ultra-drying on storability and vigour of onion seeds

Vegetable Science, 2020
Onion seeds are poor storers they have one of the loweststorability among cultivated crops. Seed moisture is one ofthe critical factors which determines the seed storability.The effect of ultra-drying of onion seeds on seed storabilityand seed vigour was studied.
Vishwanath Yalamalle, Khade, Yogesh, Singh, Major   +2 more
openaire   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Effect of different treatment on removing seed dormancy to induction of seed emergence and vigour in some populations of four species of savory (Satureja spp.) [PDF]

علوم و فناوری بذر ایران, 2017
In greenhouse experiment, the seed samples of 8 populations of four savory sepecies as: Satureja sahendica, S.bachtiarica , S.khuzistanicaandS.hortensis were treated with cold strafication, after-ripening, physical scarification (sand paper), chemical ...
M.A. Alizadeh, A.A. Hosienpoor Ghazvini, A.A. Jafari, J. Daneshian   +3 more
doaj  

Effect of Storage and Umbel Orders on Seed Quality of European Carrot Cultivar Solan Rachna under Cold Desert Conditions of Himachal Pradesh

International Journal of Bio-Resource and Stress Management, 2023
These investigations were carried out to study the effect of umbel orders and storage on seed quality of European carrot cv. Solan Rachna produced and stored in cold desert conditions at RHRSS, Tabo, Lahaul and Spiti, HP during 2008-2012.
Ashok K. Thakur, Amit Vikram, H. S. Kanwar, R. K. Bhardwaj   +3 more
doaj