Results 71 to 80 of about 2,342,936 (309)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Nutrient uptake, Yield and Quality of Linseed (Linum usitatissimum L.) as affected by Fertility Levels and Seed Rates in Dryland Condition of Eastern Uttar Pradesh

open access: yesInternational Journal of Bio-Resource and Stress Management, 2023
A field trial was conducted during the rabi season of 2006 and 2007 at the Agronomic Research farm,, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi to assess the nutrient uptake, yield and quality of linseed as affected by ...
Rang Lal Meena   +3 more
doaj  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Seed yield and seed yield components in melon genotypes with the different sex forms [PDF]

open access: yes, 2016
Zbornik: [https://www.elibrary.ru/item.asp?id=25829551]
Girek, Zdenka   +6 more
openaire  

Correlation Analysis for Seed Yield and Its Contributing Traits in Isabgol Genotypes

open access: yes, 2017
The present investigation was carried out at main experiment station Horticulture, Department of Horticulture, NDUA&T, Kumarganj, Faizabad (U.P.) to study the correlation analysis for seed yield and its contributing traits on 42 genotypes of Isabgol. The
Deen Dayal Singh   +9 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Hybrid rice seed production and yield evaluation [PDF]

open access: yes, 2007
At SPR, 8 combinations of F1 hybrid were transplanted to produce F1 seed. Average grain yield between 191-261 kg./rai with 37.74-42.68 percent filled grain had been obtained. F1 combination designated SPR06138H gave highest grain yield of 261 kg./rai. At
Bang-orn Thammasamisorn   +5 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Revealing Seed Coat Colour Variation and Their Possible Association with Seed Yield Parameters in Common Vetch (Vicia sativa L.)

open access: yesInternational Journal of Agronomy, 2016
The seed coat colour variation of 70 common vetch genotypes were determined by using uniform colour scale (L⁎a⁎b⁎) and their possible correlation with seed yield parameters including the number of pods per plant, the number of seeds per pod, pod ...
Gulgun Yildiz Tiryaki   +2 more
doaj   +1 more source

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