Results 131 to 140 of about 820,864 (392)
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Sustainable Intensification of Olive Agroecosystems via Barley, Triticale, and Pea Intercropping
In the Mediterranean basin, olive cultivation occupies the largest share of agricultural land, due to the region’s favorable soil and climatic conditions.
Andreas Michalitsis +4 more
doaj +1 more source
N fertilization has a substantial influence on sunflower (Helianthus annuus L.) seed yield and quality. It was also well established that high-yielding sunflower hybrids had more N requirement than old cultivars such as open-pollinated ones.
H. Özer, T. Polat, E. Öztürk
doaj +1 more source
Vermont Organic Corn Silage Performance Trial Results [PDF]
In 2010, the University of Vermont Extension conducted short and long season organic corn silage variety evaluations in cooperation with Vermont Technical College (VTC) and Organic Valley Farmers Advocating for Organics Program (FAFO). The purpose of the
Cummings, Erica +4 more
core +1 more source
EFFECT OF BOTANICALS SEED PRIMING ON YIELD AND YIELD COMPONENTS OF MALT BARLEY (Hordeum vulgare L.)
Abebe Megersa +2 more
openalex +1 more source
The influence of row spacing on seed yield, yield components and seed quality of alfalfa [PDF]
In order to determine the influence row spacing has on yield, yield components and the quality of alfalfa in agro-ecological conditions of south Serbia, a three year long research has been conducted, testing the NS Novosadjanka H-11 cultivar of alfalfa.
Beković, Dragoljub +4 more
openaire
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Evaluation of fruit and seed diversity and characterization of carob (Ceratonia siliqua L.) cultivars in Algarve region [PDF]
The genetic diversity of 15 carob ( Ceratonia siliqua L.) cultivars located in an experimental field from Algarve (Portugal) was evaluated over 7 years using 12 fruit and seed phenotypic characters, in order to characterize carob cultivars. The values
Barracosa, Paulo +2 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Relationships between Structures Components of Yield and Seed Yield in Chickpea
The chickpea (Cicer arietinum L.) is from the oldest and most important grain legume crops grown widely in the world under different environmental conditions. In the present investigation were included 30 accessions with local and Israeli origin.
Sofiya Petrova, Stanislav Stamatov
doaj

